OBJECTIVE This study aimed to compare the clinical and radiologic outcomes of patients with subaxial cervical injury who underwent anterior cervical discectomy and fusion (ACDF) with autologous iliac bone graft or polyetheretherketone (PEEK) cages using demineralized bone matrix (DBM). METHODS From January 2005 to December 2010, 70 patients who underwent one-level ACDF with plate fixation for...

When anterior reduction fail in the surgical treatment of cervical bilateral facet fracture-dislocation with concomitant disc extrusion, it is necessary to perform a reduction using a posterior approach and then a third anterior procedure is often necessary to accomplish the anterior reconstruction. This presents difficulties for both patients and surgeons because of the need for frequent posit...

We reviewed the biological elements supporting the usefulness of a specifically designed particulate form of demineralized bone matrix (DBM) with spinal fusion, and report some limitations of its use described in the medical literature and in the interbody space using a cadaveric biomechanical model. A literature review and description of the techniques used to augment spinal fusion are present...

STUDY DESIGN The bone union rate after lumbar interbody fusion (LIF) using titanium (Ti) or polyetheretherketone (PEEK) cages was investigated retrospectively. OBJECTIVE To assess whether the PEEK cage is superior to the Ti cage in terms of bone union after LIF. SUMMARY OF BACKGROUND DATA We previously reported that the formation of vertebral endplate cysts is useful for predicting nonunion...

OBJECTIVE It remains debatable whether cervical spine fusion cages should be filled with any kind of bone or bone substitute. Cortical and subcortical bone from the anterior and posterior osteophytes of the segment could be used to fill the cage. The purposes of the present study are to evaluate the clinical outcomes and radiological outcomes including bone fusion and subsidence that occurred a...

BACKGROUND CONTEXT Recent literature has raised some apprehensions with regard to the usage of cervical cages. PURPOSE Radiological review of cases performed at our institution with a novel cage made of polyetheretherketone (PEEK). STUDY DESIGN Retrospective study. METHODS A retrospective review of the first 15 consecutive cases of single-level anterior cervical interbody fusion using the...

Abstract Background We developed a porous Ti alloy/PEEK composite interbody cage by utilizing the advantages of polyetheretherketone (PEEK) and titanium alloy (Ti alloy) in combination with additive manufacturing technology. Methods Porous cages were manufactured using various controlled porosities. Anterior intervertebral lumbar fusion posterior augmentation performed at three vertebral levels...

BACKGROUND We evaluated the fusion efficacy and clinical outcomes of a cage containing a biphasic calcium phosphate ceramic (Triosite) in treating cervical spondylosis. METHODS We randomly divided 100 patients with cervical spondylosis undergoing anterior discectomy with interbody polyetheretherketone (PEEK) fusion into 2 groups in the past 2 years: group A (n = 50), PEEK cage containing a bi...

Spinal fusion and bone defect after injuries, removal of bone tumors, and infections need to be repaired by implantation. In an aging society, recovery from these procedures is often difficult. In this study, we found that injection of SPG-178 leads to expression of several bone marker genes and mineralization in vitro, and revealed a significantly higher degree of newly formed bone matrix with...

BACKGROUND Anterior interbody fusion of the cervical spine have become the gold standard for treating spinal diseases, hence the aim of this study was to compare long term follow up results in patients with cervical disk disease treated with anterior PEEK cage implantation and without it in anterior approach. METHODS Retrospectively 63 patients with known cervical discogenic disorders who wen...