نتایج جستجو برای: penfluridol
تعداد نتایج: 60 فیلتر نتایج به سال:
The effects of local anesthetics were examined on a family of transiently expressed neuronal calcium channels. Fomocaine, a local anesthetic containing a morpholine ring, preferentially blocked (Y,~ channels (Ki = 100 PM), and had a lower affinity (3to 15fold) for (Y,~, (Y,~, and cz,c channels. Block was incompletely reversible, followed I:1 kinetics, and did not affect steady-state inactivatio...
Immune consequences of penfluridol treatment associated with inhibition of glioblastoma tumor growth
Antischizophrenic neuroleptic drugs of the diphenylbutylpiperidine class, which includes pimozide, fluspirilene, penfluridol, and clopimozide, inhibit [3H]nitrendipine binding with IC50 values of 13-30 nM. This inhibition involves receptors for the verapamil/prenylamine class of calcium channel antagonists. These diphenylbutylpiperidines also inhibit potassium-induced calcium-dependent contract...
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