Embryonic development requires generating cell types at the right place (spatial patterning) and the right time (temporal patterning). Drosophila neuroblasts undergo stem cell-like divisions to generate an ordered sequence of neuronal progeny, making them an attractive system to study temporal patterning. Embryonic neuroblasts sequentially express Hunchback, Krüppel, Pdm1/Pdm2 (Pdm), and Castor...

Medicare policymakers are considering testing population-based disease management (PDM) programs under fee-for-service (FFS) Medicare as a way to improve health and cost outcomes for selected subgroups of chronically ill beneficiaries. This paper provides a brief overview of how PDM programs are evolving in the private sector and describes how they differ from other approaches already being tes...

This research paper briefly describes the industrial contributions of Product Data Management in any organization’s technical and managerial data management. Then focusing on some current major PDM based problems i.e. Static and Unintelligent Search, Platform Independent System and Successful PDM System Implementation, briefly presents a semantic based solution i.e. I-SOAS. Majorly this researc...

participatory conservation, as bottom-up management, is currently the most acceptable modelfor management of protected areas across the world. social context is a central issue in the sustainablemanagement of conservation areas. it is also crucial to introducing participatory conservation. the newapproach therefore recognizes rural communities as key partners in biodiversity management and seek...

Due to the development of science and technology, the computer has become a useful tool for supporting engineering activities in product design. Many computer aided tools such as CAD/CAM, product data management (PDM), product life cycle assessment (PLA), etc., have been popularly used in industry for reducing product development lead-time and increasing total product quality. However, the nume...

A hierarchical deployment of distributed product lifecycle management system in collaborative product development Yuan-Ping Luh a , Chih-Chin Pan b & Chih-Hsing Chu c a Institute of Manufacturing Technology , National Taipei University of Technology , Taipei, Taiwan b PDM/PLM Division , Alpha Precision Instrument Corporation , Taipei, Taiwan c Department of Industrial Engineering and Engineerin...

The paper gives a comprehensive overview and a classification of the fundamentals and the current state of the art of Product Data Management (PDM) technology regarding the support of distributed product development. Based on experiences and results of actual industrial projects, the requirements for distributed product development are presented. Considering these demands, different application...

Urethrocutaneous fistula (UCF) is a common complication of hypospadias surgery for severe hypospadias. We report our experience in the management of UCF following hypospadias surgery with a prepuce-degloving method (PDM). Our study included 87 patients who developed UCF after hypospadias repair from May 2001 to December 2011. Either simple closure or PDM was performed to repair the fistula. In ...

POU transcription factors participate in cell-identity decisions during nervous system development, yet little is known about the regulatory networks controlling their expression. We report all known Drosophila POU genes require castor (cas) for correct CNS expression. drifter and I-POU depend on cas for full expression, whereas pdm-1 and pdm-2 are negatively regulated. cas encodes a zinc finge...