Background Immunotherapy with T cells or bispecific T cell engagers is one promising approach to improve outcomes for patients with CD19-positive hematological malignancies. We had previously shown that T cells expressing bispecific T cell engagers that recognize CD19 and CD3 (CD19-ENG T cells) are activated in an antigen dependent manner, recruit resident T cells to tumors, and have anti-tumor...

In his book The Law of Peoples, John Rawls described an international society inwhich there are enemies and friends seeking their goals by deferent means.Rawls introduced us principles as the fundamental rights of every people. Thepeople who reserve these rights can sustain in the world. Although this theoryis supposed to be part of liberal foreign policy, the peoples Rawls talks aboutare not n...

JianGang Wang,* YaLi Wang,* FangLi Guo, ZhiBo Feng, XiangFang Wang, and ChengBiao Lu Henan Province Key Laboratory of Brain Research, Xinxiang Medical University, Xinxiang, Henan, Peoples Republic of China; Department of Pathophysiology, Xinxiang Medical University, Xinxiang, Henan, Peoples Republic of China; Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang, Hena...

The health and social conditions of First Nations, Inuit, and Métis peoples in Canada remain important policy concerns. The life course has been proposed by some as a framework for analysis that could assist in the development of policies that would improve the economic and social inclusion of Aboriginal peoples. In this paper we support the goal of applying a life-course perspective to policie...