BACKGROUND The aim of this meta-analysis was to compare the long-term survival, mortality, morbidity and the operation-related events in patients with periampullary and pancreatic carcinoma undergoing pylorus-preserving pancreaticoduodenectomy (PPPD) and pylorus-resecting pancreaticoduodenectomy (PRPD). METHOD A systematic search of literature databases (Cochrane Library, PubMed, EMBASE and W...

Carcinoma of the pancreas is now the fourth most common malignancy in many parts of the world. It is the major neoplasm in the hepato-biliary system which presents frequently as inoperable. It responds poorly to tele-radiotherapy and even bypass surgery gives the patient a very short time of relief. A search of the literature reveals the present dismal progress, even though the resection rate i...

The results of operations on 129 cases of periampullary carcinoma performed in our department during the period from January 1969 to June 1983 were studied. The rates of resection in ampullary carcinoma and inferior bile duct carcinoma were high, while the rate in pancreas head carcinoma was low. The operative mortality in resected cases was as low as 4. 3%. The number of longer survival for ov...

It is difficult to distinguish between carcinoid tumors of the pancreatic head and periampullary region and carcinomas preoperatively. Between 1996 and 2002, 125 consecutive pancreaticoduodenectomies done by us for periampullary tumors (14 carcinoids, 111 carcinomas) were analyzed. Patients with carcinoid tumors had significantly younger mean age (48 vs. 54 years), longer history (32 vs. 8 week...

BACKGROUND The early determination of premalignant lesions of pancreas can prevent unnecessary excessive surgical procedures and can reduce morbidity and mortality. Pancreatic intraepithelial neoplasia-3 (PanIN-3) is a preinvasive form of adenocarcinoma (carcinoma in situ). PanINs have not taken place in the literature of radiology yet, it should be considered in differential diagnosis of pancr...

CONTEXT Only a few studies are available in the literature regarding the AgNOR (argyrophilic nucleolar organizer region) count in pancreatic adenocarcinoma but studies on the SAPA (subjective AgNOR pattern assessment) score are completely lacking. OBJECTIVE We attempted to estimate the AgNOR count and the SAPA score in carcinoma of the pancreatic head including periampullary tumors and to cor...

CONTEXT Acute recurrent pancreatitis still poses diagnostic difficulties. The coexistence or moreover the causative relationship of carcinoma of the ampulla of Vater and acute recurrent pancreatitis is fairly rare. CASE REPORT We present a case of carcinoma of the ampulla of Vater that presented with acute recurrent necrotizing pancreatitis complicated with pseudocysts. A diagnosis of maligna...