INTRODUCTION Epidemiological studies show that individuals with periodontitis have a radically amplified threat to develop cardiovascular disease. CRP& TNF-α, are acute phase proteins monitored as a marker of inflammatory status, which have been identified as a major risk factor for atherosclerotic complications. Elevated CRP & TNF-α level in periodontitis patients have been reported by several...

OBJECTIVE Recent studies point to the clinical and research utility of saliva as a valuable diagnostic aid for monitoring periodontal health. The objectives of this study were to detect novel biomarkers attributed to chronic inflammation in saliva and to determine if the levels of these markers correlate with severity of periodontitis and with standard obesity measures in participants in a peri...

In periodontics and implant dentistry, traditional clinical criteria are often insufficient for determining sites of active disease, for monitoring quantitatively the response to therapy or for measuring the degree of susceptibility to future disease progression. Saliva as a mirror of oral and systemic health is a valuable source for clinically relevant information because it contains biomarker...

Periodontal diseases are characterized by a complex set of biologic interactions between a diverse and dynamic microbial ecosystem and the host's multifaceted and responsive immune and inflammatory machinery. Such interactions between microbial pathogens and various host response systems play a critical role in the development and progression of periodontal disease via the release of inflammato...

Abstract Periodontal diseases are chronic of oral cavity comprising inflammatory conditions which effect the supporting structures dentition. It is a multifactorial disease also known to be affected by genetic and environmental factors. However, some clinical parameters such as probing depth, attachment level, plaque index, bleeding on radiographic assessment alveolar bone assess severity disea...

Background: Observations from several epidemiologic and clinical studies suggest that psychological stress has a role in the etiology and progression of periodontal diseases (PD). The aim of the present study was to systematically analyze the influence of stress on periodontal disease reported in various case control, cross sectional and prospective clinical trials. The focused question analyze...

background: chronic renal failure patients undergoing hemodialysis are susceptible to periodontal diseases due to systemic complications of the disease and using different drugs. the present study investigated the periodontal status of patient’s who underwent hemodialysis, in babol, northern iran. methods: one-hundred-fifteen hemodialysis patients (63 males, 52 females) with the mean age of 47....

Periodontal disease is perhaps the most common infectious disease in humans. Gingival crevicular fluid (GCF) is a local inflammatory exudate of the periodontal tissues. Its composition greatly varies between health and periodontal disease. GCF collection is rapid and noninvasive, but previous approaches aiming to analyze its composition have mainly involved single protein biomarkers. The aim of...

Periodontal disease and rheumatoid arthritis are both inflammatory diseases. It is well known that there are associations between periodontitis and other systematic diseases like cardiovascular disease, diabetes mellitus and alterations during pregnancy. This review analyses the literature available dealing with the relationship between periodontal disease and rheumatoid arthritis. Periodontiti...

the aim of the present study was to examine the periodontal condition of an adult population in three isolated regions in greece and to determine the association of periodontal disease with several demographic, behavioral and environmental factors.the study population consisted of 640 individuals, aged 20 to 69 years from three isolated regions. the following indices were assessed: pocket depth...