Periodontal diseases are characterized by alveolar bone absorption and destruction of periodontal ligament and cementum and are the main causes of tooth loss in adults. This series of diseases is harmful to both human oral and body health. Although periodontitis is under control because of the implementation of conventional treatment modalities, regenerating damaged periodontal tissues remains ...

Title: Xenografts and Periodontal Regeneration. Background: The goal of periodontal therapy is to regenerate a functional attachment apparatus. However, the extent of regeneration is variable, and depends on a variety of biologic and procedural factors. In this review, we summarize the current literature describing the use of xenografts for periodontal regeneration. Methods: An electronic searc...

Inflammatory periodontal disease is a major cause of loss of tooth-supporting structures. Novel approaches for regeneration of periodontal apparatus is an area of intensive research. Periodontal tissue engineering implies the use of appropriate regenerative cells, delivered through a suitable scaffold, and guided through signaling molecules. Dental pulp stem cells have been used in an increasin...

Introduction Periodontal tissue is a complete and complex system not only includes cementum/periodontal complex, but also periodontal/alveolar complex which is more significant for tooth regeneration. Numerous therapeutic measures have been utilized over the years in an attempt to achieve predicable periodontal regeneration. However, limitations of current regeneration modalities in both predic...

In February 2008 the European Academy of Periodontology (EAP), a standing committee of the European Federation of Periodontology (EFP), invited seventy-three researchers and clinical experts from Europe and overseas for a 5-day consensus meeting on “Contemporary Periodontics.” Five working sessions covered the topics “Innovations in Periodontal Practice,” “Periodontal Tissue Engineering and Reg...

Several growth factors have been used in tissue regeneration therapy. Here we describe the use of an autologous blood clot combined with gelatin for teeth affected by severe periodontitis and vertical root fracture treated using three oral surgical procedures: periodontal flap surgery, intentional tooth replantation (IR), and tooth autotransplantation. Treatment with a blood clot improved the c...

The periodontal researchers and clinicians, in an effort to develop effective regenerative therapies, have sought to understand key events involved in the regeneration of periodontium. Polypeptide growth factors are a class of natural biological mediators which regulate key cellular events in tissue repair. Platelet-derived growth factor (PDGF) is the most thoroughly studied growth factor in pe...

Virtually all types of periodontal disease are caused by periodontal pocket infections, although several other factors, including trauma, aging, systemic diseases, genetics, etc., can contribute to the destruction of the periodontium (1, 18, 31, 52, 60, 107, 128, 127, 194). Repair of the periodontium and the regeneration of periodontal tissues remains a major goal in the treatment of periodonta...

various materials and techniques have been used in the treatment of periodontal disease to achieve regeneration of lost periodontal tissues including cementum, periodontal ligament (pdl) and alveolar bone. the composition, regenerative potential, application and therapeutic characteristics of several regenerative materials have been evaluated in the present study

Potential applications for gene-based tissue engineering therapies in the oral and maxillofacial complex include the delivery of growth factors for periodontal regeneration, pulp capping/dentin regeneration, and bone grafting of large osseous defects in dental and craniofacial reconstruction. Part 1 reviewed the principals of gene-enhanced tissue engineering and the techniques of introducing DN...