PURPOSE The aim of this study was to find an optimal range of activated clotting time (ACT) during off-pump coronary artery bypass surgery (OPCAB) yielding ischemic protection without the risk of hemorrhagic complications in patients with recent exposure to dual antiplatelet therapy. MATERIALS AND METHODS Three hundred and five patients who received aspirin and clopidogrel within 7 days of is...

The incidence of ischaemic heart disease (IHD) is increasing. The patients with IHD with or without interventions coming for non-cardiac surgical procedures are also increasing. These patients have increased risk of myocardial ischaemia, myocardial infarction (MI), conduction disturbances, morbidity and mortality during the peri-operative period. The risks of these events are even higher in pat...

BACKGROUND Aspirin administration before cardiac surgery represents a balance between preventing perioperative thrombotic events and promoting surgical bleeding. Clear evidence to guide the preoperative use of aspirin in patients undergoing cardiac surgery is lacking.This systematic review and meta-analysis was performed to evaluate the efficacy and safety of preoperative aspirin, in patients u...

Letter by Galyfos et al Regarding Article, “Periprocedural Myocardial Infarction After Carotid Endarterectomy and Stenting: Systematic Review and Meta-Analysis” To the Editor: We have read with great interest the meta-analysis by Boulanger et al, where the authors conclude that the perioperative risk for myocardial infarction (MI) after carotid endarterectomy (CEA) and carotid angioplasty with ...

INTRODUCTION Years ago, patients with recent myocardial infarction (MI) were reported to be at high risk of reinfarction (27%) and death after surgery. Therapy has changed in the 3 decades since those reports, so we reexamined that risk as well as other cardiac comorbidities and surgical work values in predicting adverse outcome. METHODS We used the National Surgical Quality Improvement Progr...

The encapsulation of polyoxometalates within the large pores of the Zr(iv) biphenyldicarboxylate UiO-67 metal-organic framework has been achieved, for the first time, by direct solvothermal synthesis. The resulting POM@UiO-67 composite materials were fully characterized by XRPD, IR, MAS NMR, N2 porosimetry measurements and cyclic voltammetry.

this review provides an overview of the present knowledge on the aspects of preoperative fasting with the assessment of the evidence quality. a systematic research was conducted in electronic databases in order to identify trials published between 1990 and 2014 concerning preoperative fasting, early resumption of oral intake and the effects of oral carbohydrate mixtures on gastric emptying and ...

Ligation of the left anterior descending coronary artery (LAD) is used to induce experimental myocardial infarction (MI). Most previous studies have focused on the early postoperative period, while data on mid-term follow-up are scanty. This study examined the mid-term effects of LAD ligation in 95 MI rats and 28 controls. The following parameters were evaluated: systemic blood pressure (SBP), ...

We prospectively studied changes in serum lactate dehydrogenase isoenzyme-1 (LD-1, EC 1.1.1.27) in 99 consecutive patients after either coronary artery bypass grafting (CABG, n = 61), isolated cardiac-valve replacement (n = 24), or the two procedures combined (n = 14); 86 of these had no clinical evidence of peri-operative myocardial infarction (MI). Blood was sampled immediately after surgery ...