BACKGROUND To evaluate the peripapillary choroidal thickness of a healthy Chinese population, and to determine its influencing factors. METHODS A total of 76 healthy volunteers (76 eyes) without ophthalmic or systemic symptoms were enrolled. Choroidal scans (360-degree 3.4 mm diameter peripapillary circle scans) were obtained for all eyes using enhanced depth imaging spectral-domain optical c...

PURPOSE To evaluate the peripapillary and perifoveal retinal perfusions of young healthy eyes with a tessellated fundus using optical coherence tomography (OCT) angiography. METHODS Thirty-five Chinese subjects with a tessellated fundus and 35 subjects without a tessellated fundus from a population-based cross-sectional study in Shanghai were included. All participants underwent OCT angiograp...

OBJECTIVES The aim of this study was to evaluate the peripapillary and parafoveal perfusion of young, healthy myopic subjects with spectral domain optical coherence tomography (OCT) angiography. DESIGN A prospective comparative study was conducted from December 2014 to January 2015. SETTING Participants recruited from a population-based study performed by the Eye, Ear, Nose and Throat Hospi...

1. Toranzo J, Cohen SY, Erginay A, Gaudric A. Peripapillary intrachoroidal cavitation in myopia. Am J Ophthalmol. 2005;140(4):731-732. 2. Shimada N, Ohno-Matsui K, Nishimuta A, Tokoro T, Mochizuki M. Peripapillary changes detected by optical coherence tomography in eyes with high myopia. Ophthalmology. 2007;114(11):2070-2076. 3. Freund KB, Mukkamala SK, Cooney MJ. Peripapillary choroidal thicke...

PURPOSE To assess the diagnostic efficacy of macular and peripapillary retinal thickness measurements for the staging of diabetic retinopathy (DR) and the prediction of disease progression. METHODS In this prospective study, 149 diabetic patients (149 eyes) and 50 non-diabetic control subjects were included. Baseline optical coherence tomography was employed to measure retinal thickness in th...

PURPOSE To identify the risk factors for development of peripapillary retinal splitting (schisis) in patients with glaucoma or suspicion of glaucoma. SETTING Glaucoma Clinic, Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL. METHODS In this institutional cross-sectional study, 495 patients (990 eyes) who had undergone spectral-domain optical cohe...

PURPOSE The peripapillary retinal nerve fiber layer (RNFL) thickness pattern in the normal human eye has been well characterized using data obtained with scanning laser polarimetry and optical coherence tomography. The authors sought to characterize the normative peripapillary RNFL thickness and pattern using histologic sections obtained from healthy postmortem human eyes. METHODS Seventeen u...

BACKGROUND Peripapillary loops of venous origin are extremely rare. CASE A 55-year-old woman was referred to us for further examination of peripapillary vascular abnormalities. OBSERVATIONS Fundus examination and fluorescein angiography clearly showed a venous and an arterial peripapillary loop in both her right and left fundi. The venous loop in the right eye was in a large hairpin configu...

BACKGROUND Peripapillary intrachoroidal cavitation was described as the presence of an asymptomatic, well-circumscribed, yellow-orange, peripapillary lesion at the inferior border of the myopic conus in eyes with high myopia. CASE PRESENTATION A 66-year-old myopic Chinese man was enrolled and his multi-color imaging examination showed a well-circumscribed, caesious, peripapillary lesion coale...

BACKGROUND Inner (area adjacent to the fovea) and outer regions of the macula differ with respect to relative thicknesses of the ganglion cell layer (neurons) vs retinal nerve fiber layer (RNFL; axons). OBJECTIVE To determine how inner vs outer macular volumes relate to peripapillary RNFL thickness and visual function in multiple sclerosis (MS) and to examine how these patterns differ among e...