2/17 Clinical Features: Congenital hypothyroidism is a condition characterized by inadequate availability of active thyroid hormone to target tissues in the newborn period. It can be sporadic or inherited. In 80 to 85% of cases, congenital hypothyroidism is the consequence of thyroid dysgenesis due to absent (athyreosis), abnormally located (ectopic), or small (hypoplastic) thyroid gland (1). C...

how to cite this article: ordooei m, mottaghipisheh h, fallah r, rabiee a. cognitive outcomes for congenital hypothyroid and healthy children: a comparative study. iran j child neurol. 2014 autumn;8(4): 28-32. abstract objective early diagnosis and treatment of congenital hypothyroidism (ch) and the prevention of developmental retardation is the main goal of public health national screening pro...

Prolonged juvenile hypothyroidism results in a permanent loss in height that is related to the duration of thyroxine deficiency before adequate thyroxine replacement treatment. A 13 year old girl with severe juvenile hypothyroidism was studied prospectively. She had an undetectable serum thyroxine concentration, a height SD score of -6.6 SD, and a bone age of 5.8 years. The enlarged pituitary g...

‘Screening window’, defined as the period between the development of the abnormal test result of NBS and development of symptoms in the infant, may vary from disorder to disorder. It will be most ideal to collect sample on fourth day of life. Samples can be collected from home by trained nurse/phlebotomist. There are many riders associated with interpretation of blood samples collected in the f...

We measured free thyroxin (FT4) in dried blood samples from 10 000 euthyroid and 29 hypothyroid newborns (three with transient hypothyroidism and 26 permanent). In euthyroids, the mean FT4 concentration was 16.9 (SD 4.5) pmol/L. Preterm babies had low concentrations of FT4, and values were closely related to birth weight when less than 2500 g. Assay of blood-spot FT4 appears to be specific as a...

Background and Objective: Chronic kidney disease (CKD)  determined by permanent kidney damage. Due to the similarity of clinical symptoms of hypothyroidism with CKD, hypothyroidism may be neglected and remain untreated. The goal of our study was to evaluate the rate of hypothyroidism in CKD patients who need hemodialysis. Materials and Methods: This is a cross-sectional research. The sampling ...