Ketorolac is a non-steroidal anti-inflammatory drug. Dextran conjugates of ketorolac (KD) were synthesized and characterized to improve ketorolac aqueous solubility and reduce gastrointestinal side effects. An N-acylimidazole derivative of ketorolac (KAI) was condensed with a model carrier polymer, dextran of different molecular masses (40000, 60000, 110000 and 200000). IR spectral data confirm...

In this study, we report the optimal extraction conditions for obtaining organosulfur compounds, such as cycloalliin, from garlic by using principal component analysis (PCA). Extraction variables including temperature (40~80°C), time (0.5~12 h), and pH (4~12) were investigated for the highest cycloalliin yields. The cycloalliin yield (5.5 mmol/mL) at pH 10 was enhanced by ~40% relative to those...

AIM Early prediction of prognosis after out-of-hospital cardiac arrest (OHCA) remains difficult. High blood lactate or low pH levels may be associated with poor prognosis in OHCA patients, but these associations remain controversial. We compared blood lactate and pH levels in OHCA patients transferred to our hospital to measure their prognostic performance. METHODS We investigated the associa...

Sucrose density gradient analyses of pH 5.5 and pH 7.4 extracts from rat liver nucleoli revealed the presence of two broad peaks of approximately 60S and 80S, and 60S and 80-100S, respectively. Ribonucleoprotein (RNP) particles containing precursor ribosomal RNA in these peaks have been characterized by electron microscopy and RNA analyses. Spherical particles only were found in the 60S peak of...

The adverb ”then” is among the most frequent English temporal adverbs, being also capable of filling a variety of semantic roles. The identification of anaphoric usages of ”then” is important for temporal expression resolution, while the temporal relationship usage is important for event ordering. Given that previous work has not tackled the identification and temporal resolution of anaphoric ”...

Our aim was to determine the effects of focal acidification in the raphe obscurus (RO) and raphe pallidus (RP) on ventilation and other physiological variables in both the awake and sleep states in adult goats. Through chronically implanted microtubules, 1) a focal acidosis was created by microdialysis of mock cerebrospinal fluid (mCSF), equilibrated with various levels of CO2, and 2) medullary...

Pasundan cattle are one of the Indonesian domestic resources animal-genetic materials that need to be developed and conserved. The aims this study were evaluate characteristics sperm potential production frozen semen bulls. Ten bulls divided into two groups based on their fresh motilities. grouped motilities group A (70-79%) B (80-89%). Secondary data collected confirmed with primary data. volu...

Two field experiments (Spring, 1974 and 1975) were conducted on Myakka fine sand to determine the effect of lime and nitrogen source on the development of Fusarium wilt of cucumber and watermelon. The same site, with the same experimental design, was used for each experiment. In both experiments, gross yields were increased and wilt development decreased by raising the soil pH with hydrated lim...