The imaging of distributed sources with near-field coded aperture (CA) remains extremely challenging and is broadly considered unsuitable for single-photon emission computerized tomography (SPECT). This study proposes a novel CA SPECT reconstruction approach and evaluates the feasibilities of imaging and reconstructing distributed hot sources and cold lesions using near-field CA collimation and...

introduction: poor sensitivity and poor signal to noise ratio because of low injected thallium dose and presence of scattered photons are the main problems in using thallium in scintigraphic imaging of the heart. scattered photons are the main cause of degrading the contrast and resolution in spect imaging that result in error in quantification. thallium decay is very complicated and photons ar...

PURPOSE Over the last ten years, there has been an extensive growth in the development of microSPECT imagers. Most of the systems are based on the combination of conventional, relatively large gamma cameras with poor intrinsic spatial resolution and multipinhole collimators working in large magnification mode. Spatial resolutions range from 0.58 to 0.76 mm while peak sensitivities vary from 0.0...

introduction: attenuation correction is a useful process for improving myocardial perfusion spect and is dependent on activity and distribution of attenuation coefficients in the body (attenuation map). attenuation artifacts are a common problem in myocardial perfusion spect. the aim of this study was to compare the effect of attenuation correction using different attenuation maps and different...

Background: Single-photon emission computed tomography (SPECT) imaging is an important diagnostic tool for the early detection of the loss of nigrostriatal dopaminergic neurons in Parkinson’s disease (PD) and similar neurodegenerative disorders. Visualization and quantification of dopamine transporter (DAT) binding in the striatum is an established diagnostic tool to detect nigrostriatal dopami...

Background: In myocardial perfusion SPECT imaging, images are degraded by photon attenuation, the distance-dependent collimator, detector response and photons scatter. Filters greatly affect quality of nuclear medicine images Materials and Methods: A phantom simulating heart left ventricle was built. About 1mCi of 99mTc was injected into the phantom. Images were taken from this phantom. Some fi...

The purpose of this study is to investigate the optimal reference geometry for gamma camera calibration. Yet another question of interest was to assess the influence of the number of 3D Ordered Subsets Expectation Maximization (3D-OSEM) updates on activity quantification for SPECT imaging with 177Lu. The accuracy of 177Lu activity quantification was assessed both in small and in large objects. ...

background: in myocardial perfusion spect imaging, images are degraded by photon attenuation, the distance-dependent collimator, detector response and photons scatter. filters greatly affect quality of nuclear medicine images materials and methods: a phantom simulating heart left ventricle was built. about 1mci of 99mtc was injected into the phantom. images were taken from this phantom. some fi...

Quantitative measurement of myocardium perfusion is possible with single photon emission computed tomography (SPECT) using a semiconductor detector. However, accumulation of 99mTc-tetrofosmin in the liver may make it difficult to assess that accurately in the inferior myocardium. Our idea is to reduce the high accumulation in the liver by using dynamic SPECT imaging and a technique called time ...

  Introduction: Attenuation correction is a useful process for improving myocardial perfusion SPECT and is dependent on activity and distribution of attenuation coefficients in the body (attenuation map). Attenuation artifacts are a common problem in myocardial perfusion SPECT. The aim of this study was to compare the effect of attenuation correction using different a...