using MRI to evaluate serial changes in myocardial contractile function (EDV, ESV, EF and regional thickness and thickening) using RF tagging to assess changes in myocardial stress and strain using magnetic resonance angiography to evaluate changes in the luminal size and in plaque morphology (and possibly character) in larger arteries such as the aorta, carotids and iliacs assessing regional m...

The number of couples seeking consultation for infertility problems has steadily increased over the past decade, affecting 10%-15% of the sexually active population. Abnormal semen production, a male factor infertility (MFI), is thought to be the cause of up to 50% of all infertilities in developed countries. There are potentially many different causes of male infertility, including hormonal, a...

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after the boom of pharmacological research during the 1950s, mainly as a result of the screening technique, the identification of active molecules, their reshaping by means of pharmaco-chemical drug design, and the creation of extremely efficacious and successful medicines, the pharmaceutical world sought a new source of inspiration. such biota as the tropical forest, a quantity of plants credi...

BACKGROUND The pharmaceutical industry employs >350 000 people worldwide in operations including research and development (R&D), manufacturing, sales and marketing. Workers employed in R&D and manufacturing sectors are potentially exposed to drug substances in the workplace that are designed to modify physiology and also to chemical precursors that are potentially hazardous to health. Pharmaceu...