Heat, acid, base, UV radiation and oxidation stress methods were applied to study the stability of cough-cold products containing acetaminophen, phenylephrine or phenylpropanolamine hydrochloride and chlorpheniramine maleate. Liquid chromatography coupled with mass spectrometry was used to analyze the degraded samples and obtain molecular weights information. Different volatile buffers (ammoniu...

We report two cases of serious intracerebral haemorrhage occurring in young women following their first use of oral medications containing catecholaminergic agents (phenylpropanolamine in combination with ephedrine or pseudoephedrine). Both women were previously well, and there was no evidence for systemic vasculitis, coagulopathy, aneurysm or arteriovenous malformation. Angiography in both cas...

This analysis explores (1) whether plan demographic characteristics would affect individual participant contribution rates and target-date fund investments and (2) equity glide paths for participants in relation to plan demographics by considering target replacement income and its success rate. PLAN DEMOGRAPHIC CHARACTERISTICS IN PARTICIPANT CONTRIBUTION RATES: This study finds empirical eviden...

in this study, different derivative spectrophotometric methods are proposed for the simultaneous determination of chlorpheniramine maleate (cp), phenylephrine hcl (pe) and phenylpropanolamine hcl (pp) in their ternary mixtures and in pharmaceutical dosage forms. spectra of single component and ternary mixtures of various concentrations and combinations from zero- to fourth-derivation were obtai...

I've been concerned about my weight all through college. I have what you would call a subclinical eating disorder that never goes so far as anorexia or bulimia. My question is: I have been using diet suppressants (phenylpropanolamine HCL 75mg) bought over the counter for months. Sometimes I don't take them for a week, but usually I take one dose a few times a week. I know it's not recommended t...

A capillary electrophoretic method, which allowed the detection and separation of the active principles of Catha edulis, i.e. cathinone, cathine and phenylpropanolamine, was developed. A suitable internal standard (nicotinamide), which permitted the quantification of the analytes reducing the variability of the migration times due to EOF changes, was identified. The analytical method was valida...

I've been concerned about my weight all through college. I have what you would call a subclinical eating disorder that never goes so far as anorexia or bulimia. My question is: I have been using diet suppressants (phenylpropanolamine HCL 75mg) bought over the counter for months. Sometimes I don't take them for a week, but usually I take one dose a few times a week. I know it's not recommended t...