variations in phosphatidate phosphohydrolase (pap) activity and triacylglycerol concentration were measured in pregnant and hormone-treated non-pregnant female rats. pap activity in adipose tissue was elevated by 61% during pregnancy. the increase in the enzyme activity was paralleled with a rise in serum triacylglycerol concentration (44%). estradiol injecting into non-pregnant rats increased ...

Feeding rats with sorbitol, fructose, glycerol and ethanol increases the concentration of serum corticosterone without significantly altering the concentration of insulin. This increase appears to be partly responsible for the increases in the hepatic activity of phosphatidate phosphohydrolase (compared with rats fed glucose or 0.9% NaCI) that has been reported [Sturton, Pritchard, Han & Brindl...

objective(s) phosphatidate phosphohydrolase (pap) catalyzes the dephosphorylation of phosphatidic acid to yield pi and  diacylglycerol. two different forms of pap in rat hepatocyte have been reported. pap1 is located in cytosolic and microsomal fractions and participates in the synthesis of triacylglycerols, phosphatidylcholine, and phosphatidylethanolamine, whereas the other form of phosphatid...

the effects of steroid hormones, glucagon and insulin on rat liver phosphatidate phosphohydrolase (pap) activity were studied both in vitro and in vivo. incubation of rat hepatocytes with each hormone showed that dehydroepiandrosterone (dhea), progesterone and testosterone increase pap activity by 44.6, 37 and 36.9%, respectively. estradiol, however, decreased enzyme activity by 13.6% under the...

Kidney glucose 6-phosphatase has been shown to catalyze inorganic pyrophosphatase and inorganic pyrophosphate-, cytidine diphosphate-, cytidine triphosphate-, and mannose 6-phosphate-glucose phosphotransferase reactions. The catalytic properties of phosphohydrolase and phosphotransferase activities of the kidney enzyme were found to be very similar to those of corresponding hepatic activities (...

A nucleotide phosphohydrolase (adenosine triphosphatase), which is associated with vaccinia virus cores, has been solubilized and shown to be deoxyribonucleic acid dependent.