Hydroa vacciniforme is a rare idiopathic photodermatosis uncommon in dark skinned patients, which usually begins in childhood before the age of 10 years old and disappear in adolescence , it begins symmetrically in photo exposed areas as a sensation of skin burning in less than 24 hours of sun exposition , and then a vesicular rash develops , become umbilicated and secondarily crusted. Within w...

BACKGROUND Actinic prurigo (AP) is a type of photodermatosis, the pathophysiology of which has not been determined. AP has been suggested to be a hypersensitivity reaction to the presence of eosinophils and the local production of IgE. MATERIAL AND METHODS Descriptive study, using paraffin blocks of tissue that have been diagnosed with AP from the Dermopathology department, Hospital General D...

Phototoxicity and photoallergy are different expressions of an abnormal skin reaction from the exposure to light, usually enhanced by endogenous or exogenous substances that are selectively activated by solar radiation. This can occur with artificial light sources (sun lumps used for aesthetic or therapeutic purposes or ultraviolet (UV) sources in occupational settings), but mostly occur on sun...

Chronic active Epstein-Barr virus (EBV) disease (CAEBV) is a systemic EBV-positive lymphoproliferative disorder characterized by fever, lymphadenopathy, and splenomegaly. Patients with CAEBV may present with cutaneous symptoms, including hypersensitivity to mosquito bites and hydroa vacciniforme (HV)-like eruptions. HV is a rare photodermatosis characterized by vesicles and crust formation afte...

BACKGROUND Actinic prurigo is an idiopathic photodermatosis, the pathophysiology of which has been hypothesized to involve subtype IV type b (Th2) hypersensitive response, whereby IL4, IL5, and IL13 are secreted and mediate the production of B cells, IgE, and IgG4. OBJECTIVES To examine the association of serum IgE levels and the clinical severity of injuries. METHODS This case-control stud...

Actinic prurigo (AP) is a rare acquired idiopathic photodermatosis, reported most often in American Indians, but also in Caucasian and Asian populations. The skin lesions in AP predominantly affect exposed sites but may involve covered areas, and often result in postinflammatory scarring. The diagnosis of AP can be difficult and relies on a combination of history, clinical experience and invest...

68 Abstract Neuropathic itch (itching or pruritus) arises from a pathology located at any point along the afferent pathway of the nervous system. It may be related to damage to the peripheral nervous system, such as in postherpetic neuropathy, brachioradial pruritus or notalgia paresthetica. It has many clinical features similar to neuropathic pain. Patients complain of itching, which is associ...

PURPOSE Epstein-Barr virus (EBV) infects not only B cells but also T cells and natural killer (NK) cells, and T- and NK-cell lymphoproliferative diseases (T/NK-LPD) that are refractory to conventional chemotherapies may develop. To identify a molecular-targeted therapy for EBV-associated T/NK-LPDs, we investigated whether CC chemokine receptor 4 (CCR4) was expressed on EBV-infected T and/or NK ...

Purpose:Epstein–Barr virus (EBV) infects not only B cells but also T cells andnatural killer (NK) cells, and TandNK-cell lymphoproliferative diseases (T/NK-LPD) that are refractory to conventional chemotherapies may develop. To identify a molecular-targeted therapy for EBV-associated T/NK-LPDs, we investigated whether CC chemokine receptor 4 (CCR4) was expressed on EBV-infected T and/or NK cell...

© 2012 The Authors. doi: 10.2340/00015555-1235 Journal Compilation © 2012 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, We read with interest the article by von Bartenwerffer et al. (1) about a deeply tanned patient who exhibited multiple white macules on his skin after self-application of an alleged synthetic alpha melanocyte stimulating hormone (α-MSH) analogue. The names “afamelanotide”, “...