The present report describes the case of a 29-year-old man referred to our service for TMJ pain and progressive reduction of the mouth opening. Differential diagnostics included rheumatologic diseases, monoarthritis and intraarticular lumps. In this line, a face CT scan and a MRI of TMJ were carried out in order to ensure a proper diagnosis. These tests showed a solid lesion into the joint cavi...

Diffuse type tenosynovial giant cell tumor (D-TGCT) is a locally aggressive benign proliferation. Knee joint the most commonly affected site. We present case report with 16 months follow up after recurrent surgery and postoperative radiotherapy.

This case report is concerned with a 30 year old patient diagnosed with pigmented villonodular synovitis (PVNS) in the knee. The patient underwent an orthopedic surgical operation to remove the lesions. PVNS is a rare proliferative disorder, mostly benign and affecting the knee; its aetiology remains unclear. It represents a medical challenge because of non-specific symptoms that delay the diag...

To cite: Atik A, Ozyurek S, Sivrioglu AK, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013009353 DESCRIPTION A 23-year-old man who had sustained a minor twisting injury 10 days prior, presented with right knee pain and swelling. There was no history of joint problems, infection or bowel problems, nor was there a family history of arthritis. Physical exa...

We describe a surgical treatment for popliteal cyst in a 41-year-old woman affected by diffuse pigmented villonodular synovitis (PVNS) of the knee with extra-articular spreading. The treatment consists of an arthroscopic synoviectomy followed immediately by an open removal of the cyst. At 28-month follow-up, the patient is asymptomatic and no evidence of recurrence of PVNS has been seen. We bel...

Invasion and erosion of bone in nodular synovitis (histiocytic xanthomatous granuloma, xanthoma, giant-cell tumour, benign synovioma) are found fairly frequently in circumscribed lesions of the tendon sheaths of hands and feet. Fletcher and Horn (1951) in particular called attention to this. Bone involvement in diffuse forms, namely “ pigmented villonodular synovitis, bursitis and tenosynovitis...

Cryostat section of synovial tissue from patients with rheumatoid arthritis, ankylosing spondylitis, osteoarthrosis, pigmented villonodular synovitis, and from a normal knee were studied by indirect immunofluorescence with guinea-pig antibodies to the intermediate filament proteins prekeratin, vimentin, and desmin. Staining for vimentin, but absence of prekeratin and desmin, was demonstrated in...

We describe a case of 30-year old male followed-up since the age of 6 for severe type of rare combination of polyarticular form of pigmented villonodular synovitis with hereditary malformation constellation consistent with Noonan-like syndrome. Within 20 years, the patient underwent repeated synovectomies of large joints with temporary effect only. Radiation therapy with the dose of 30 Gy in 15...