Should clinical trial pilot studies be reported? Thebane, Ma, Chu, et al. argue in their discussion of the conduct of pilot studies, that they should be published [1]. Others, such as the editorialist for The Diabetes Educator, take a more cautious approach to publishing pilot studies [2]. I agree with those who advocate publication. I might also note that a September 27, 2012 search of “random...

Composites in 25 kg batches were compounded of cellulose nanocrystals (CNC) and thermomechanical pulp (TMP) shaped into caps at industrial facilities on a pilot-plant scale. Some the material was also injection molded plaques to compare effect laboratory-scale pilot-scale compounding poly(ethylene-co-acrylic acid) (EAA7) poly(caprolactone) composites reinforced with 10 wt% CNC TMP. The material...

The ability to predict the performance of large-scale processes is central to the rapid development of successful operations at the pilot and industrial scale. In this article, we examine the operation, at laboratory scale, of precipitation reactors and centrifuges for protein precipitate recovery and dewatering and how they might best mimic large-scale reactors and centrifuges, in this case, a...

Multi-species water quality models can be used to predict the fate and transport of contaminants such as arsenic in water distribution networks. In recent work, water quality models have been used to simulate hypothetical contamination events, estimate potential human health effects, and characterize the ability of sensors to detect contamination. Little work has been done to calibrate water qu...

Small-scale pilot projects have demonstrated that integrated population, health and environment approaches can address the needs and rights of vulnerable communities. However, these and other types of health and development projects have rarely gone on to influence larger policy and programme development. ExpandNet, a network of health professionals working on scaling up, argues this is because...