Pellitorine (1), which was isolated from the roots of Piper nigrum, showed strong cytotoxic activities against HL60 and MCT-7 cell lines. Microbial transformation of piperine (2) gave a new compound 5-[3,4-(methylenedioxy)phenyl]-pent-2-ene piperidine (3). Two other alkaloids were also found from Piper nigrum. They are (E)-1-[3',4'-(methylenedioxy)cinnamoyl]piperidine (4) and 2,4-tetradecadieno...

The efficacy of extracts from two Piperaceae species, Piper nigrum L. and P. tuberculatum Jacq. were evaluated using larvae and adults of the Colorado Potato Beetle Leptinotarsa decemlineata (Say). Young larvae and neonates were the most susceptible; a 24-h LD(50) of 0.064% extract of P. tuberculatum was determined for 4-day-old larvae, while 0.05% extract of P. nigrum reduced larval survival u...

BACKGROUND/AIM Alzheimer's disease (AD) is a progressive neurodegenerative disorder. Increased oxidative stress has been shown to be a prominent and early feature in AD. Medicinal plants with antioxidant activities have been used traditionally in the treatment of several human diseases. The present study aims to investigate the effect of Salvia triloba and Piper nigrum plant extracts on the oxi...

Piper nigrum is famous as the spices king due to its pungent quality[1]. Piper nigrum (P.nigrum) L. is a member of family Piperaceae[2-4]. The genus piper has more than 1000 species but the most well known species are P.nigrum, P.longum and P.betle; 51 cultivars of p. nigrum have been reported from the tropical and subtropical regions of India [5]. P.nigrum fruits are also used to produce white...

B.Umamaheswari & S.Rajalakshmi – Department of Microbiology, Idhaya College for women Kumbakonam. Guided by: Miss. B.Umamaheswari, M.Sc., M.Phil,-lecturer in microbiology, Idhaya College for women ABSTRACT In the present study the Indian spices extracts of Piper nigrum, Foeniculum vulgare, Syzyigum aromaticum and Elettaria cardamomum was used for antibacterial activity assay. The test organism ...

Spices have been added to foods since ancient times, not only as flavoring agents, but also as folk medicines and food preservatives. The current investigation deals with the extraction and phytochemical analysis of Syzygium aromaticum, Piper nigrum and Cinnamomum verum which are one of the most important spices used in India. The presence of phytochemicals including phytosterols, saponins, alk...

Various parts of Piper nigrum, Piper betle and Gnetum gnemon are used as food sources by Malaysians. The purpose of this study is to examine the anti-quorum sensing (anti-QS) properties of P. nigrum, P. betle and G. gnemon extracts. The hexane, chloroform and methanol extracts of these plants were assessed in bioassays involving Pseudomonas aeruginosa PA01, Escherichia coli [pSB401], E. coli [p...

Effect of oral administration (25 and 100 mg/kg body wt/day, for 20 and 90 days) of fruit powder of Piper nigrum L. on the male reproductive organs of mice, Parkes strain, was investigated. Various reproductive end points such as organs weight, histopathology, sperm parameters, sialic acid and fructose contents, and fertility indices were assessed. Histologically, testes in treated mice, except...