Power Internet of Things (IoT) is the application IoT technology in field power grid, which can better control all kinds equipment, personnel and operating environment. However, access to mass terminals brings higher requirements for terminal authentication key management IoT. And traditional public infrastructure (PKI) identity-based cryptography (IB-PKC) exist problems certificate escrow. The...

A CC chemokine, CCL18, has been previously reported to stimulate collagen production in pulmonary fibroblasts. This study focused on the role of protein kinase C (PKC) in the profibrotic signaling activated by CCL18 in pulmonary fibroblasts. Of the three PKC isoforms that are predominantly expressed in fibroblasts (PKC , PKC , and PKC ), two isoforms (PKC and PKC ) have been implicated in profi...

We investigated the protein expression of different protein kinase C (PKC) isoforms (PKC-alpha, PKC-beta1, PKC-beta2, PKC-gamma, PKC-delta, PKC-epsilon, PKC-eta and PKC-zeta) in the hippocampus of normal control mice and progressive changes in PKC isoforms expression during and after pilocarpine induced status epilepticus (PISE). We showed the reduced expression of PKC-delta, PKC-eta and PKC-ze...

Objective(s):Cyclophosphamide (CP) toxicity on testis was hampered by squid ink polysaccharide (SIP) via restoration of antioxidant ability in our previous investigations. This study investigated roles of Nrf2/ARE signal pathway in testis of treated mice. Materials and Methods: Male Kunming mice were employed to undergo treatment with SIP and/or CP. Protein levels of Nrf2, keap-1, histone deac...

Purpose: To investigate the protective effect of vitexin on smoke inhalation-induced acute lung injury (SI-ALI), and underlying mechanism action.Methods: The ALI rat model was established by inhalation in a closed chamber. Survival rate, arterial blood gas analysis, wet-to-dry weight ratio tissues, bronchoalveolar lavage fluid protein concentration, tissue histology, oxidative stress inflammati...

Induction of erythroid differentiation of murine erythroleukemia cells (MELC) by exposure to hexamethylene bisacetamide (HMBA) involves the modulation of protein kinase C (PKC) activity. Using immuno- and Northern blot techniques, we have demonstrated that MELC express a pattern of PKC isoforms which includes PKC alpha, PKC delta, PKC epsilon, PKC zeta, and PKC eta. We show that MELC resistant ...

Growth hormone (GH) is a key modulator of growth and GH over-secretion can lead to gigantism. One form X-linked acrogigantism (X-LAG), in which infants develop secreting pituitary tumors over-expressing the orphan G-protein coupled receptor, GPR101. The role GPR101 secretion remains obscure. We studied signaling pathways their effects HEK293 rat GH3 cell lines, human transgenic mice with elevat...

To elucidate the involvement of protein kinase C (PKC) isoforms in insulin-induced and phorbol ester-induced glucose transport, we expressed several PKC isoforms, conventional PKC-alpha, novel PKC-delta, and atypical PKC isoforms of PKC-lambda and PKC-zeta, and their mutants in 3T3-L1 adipocytes using an adenovirus-mediated gene transduction system. Endogenous expression and the activities of P...