The timing and magnitude of an escape reaction is often the determining factor governing a copepod's success at avoiding predation. Copepods initiate rapid and directed escapes in response to fluid signals created by predators; however little is known about how copepods modulate their behavior in response to additional sensory input. This study investigates the effect of light level on the esca...

Cytokinins promote cell division and chloroplast development in tissue culture. We previously isolated two mutants of Arabidopsis thaliana, ckh1 (cytokinin-hypersensitive 1) and ckh2, which produce rapidly growing green calli in response to lower levels of cytokinins than those found in the wild type. Here we report that the product of the CKH2 gene is PICKLE, a protein resembling the CHD3 clas...

Drug responses vary greatly among individuals due to human genetic variations, which is known as pharmacogenomics (PGx). Much of the PGx knowledge has been embedded in biomedical literature and there is a growing interest to develop text mining approaches to extract such knowledge. In this paper, we present a study to rank candidate gene-drug relations using Latent Dirichlet Allocation (LDA) mo...

Vegetative phase change in flowering plants is regulated by a decrease in the level of miR156. The molecular mechanism of this temporally regulated decrease in miR156 expression is still unknown. Most of the miR156 in Arabidopsis thaliana shoots is produced by MIR156A and MIR156C. We found that the downregulation of these genes during vegetative phase change is associated with an increase in th...

G protein-coupled receptor kinaseinteracting protein 1 (GIT1) was originally identified as an ADP ribosylation factor GTPase-activating protein (ARF-GAP) that binds Gprotein-coupled receptor kinases (GRKs) and regulates membrane trafficking (Premont et al., 1998). Subsequent studies have shown a much broader function for GIT1 and GIT2/PKL as regulators of migrationrelated processes, including a...

When a nuclear power plant is in shutdown conditions for refuelling, the reactor coolant system water level is reduced. This situation is known as mid-loop operation, and the residual heat removal (RHR) system is used to remove the decay power heat generated in the reactor core. In mid-loop conditions, some accidental situations may occur with not a negligible contribution to the plant risk, an...

OBJECTIVE Aiming at contributing to the knowledge on doses in computed tomography (CT), this study has the objective of determining dosimetric quantities associated with pediatric abdominal CT scans, comparing the data with diagnostic reference levels (DRL). MATERIALS AND METHODS The study was developed with a Toshiba Asteion single-slice CT scanner and a GE BrightSpeed multi-slice CT unit in...