The in vivo apparent diffusion tensor (ADT) of spinal cord was measured in nine rats at 2.0 T using an interleaved multi-shot echo planar imaging (EPI) diffusion sequence. A technique that combines sliding acquisition and phase correction, based on a calibration scan, to reduce ghosting artifacts in the images introduced by the strong diffusion-sensitizing gradients was described. Two rotationa...

Most diffusion imaging sequences rely on single-shot echo-planar imaging (EPI) for spatial encoding since it is the fastest acquisition available. However, it is sensitive to chemical-shift artifacts due to the low bandwidth in the phase-encoding direction, making fat suppression necessary. Often, spectral-selective RF pulses followed by gradient spoiling are used to selectively saturate the fa...

Magnetic field inhomogeneities like eddy current-related gradient fields cause geometric distortions in echo-planar imaging (EPI). This in particular affects diffusion-weighted imaging where these distortions vary with the direction of the diffusion weighting and hamper the accurate determination of diffusion parameters. The double-spin-echo preparation often used aims to reduce the cumulative ...

In order to investigate the properties of water motion within and around brain tumors as a function of tumor growth, longitudinal diffusion tensor imaging (DTI) was carried out in a rat brain glioma (C6) model. As tumors grew in size, significant anisotropy of water diffusion was seen both within and around the tumor. The tissue water surrounding the tumor exhibited high planar anisotropy, as o...

Diffusion-weighted (DW) magnetic resonance imaging (MRI) is the only technique that permits a non-invasive in vivo assessment of water molecular diffusion, which reflects tissue configuration at a microscopic level. Therefore, this technique appears to be particularly useful in monitoring brain abnormalities. However, the quantitative measurement of diffusion is not without problems, which may ...

This paper outlines the mathematical development and application of two analytically orthogonal tensor invariants sets. Diffusion tensors can be mathematically decomposed into shape and orientation information, determined by the eigenvalues and eigenvectors, respectively. The developments herein orthogonally decompose the tensor shape using a set of three orthogonal invariants that characterize...

Background: There is no consistent data on the mechanical properties of sheep intestine. OBJECTIVES: We performed a series of biaxial strain measurement experiments and extracted the constitutive model to describe the mechanical characteristics of the sheep intestinal tissue. METHODS: Eleven specimens were obtained freshly from sacrificed  sheep and the planar biaxial tests were performed on th...

We present an analysis of the magnetic anisotropy in epitaxial Ga1−xMnx As thin films through electrical transport measurements on multiterminal microdevices. The film magnetization is manipulated in 3D space by a three-axis vector magnet. Anomalous switching patterns are observed in both longitudinal and transverse resistance data. In transverse geometry in particular we observe strong interpl...

PURPOSE To develop a phantom for validating MRI pulse sequences and data processing methods to quantify microscopic diffusion anisotropy in the human brain. METHODS Using a liquid crystal consisting of water, detergent, and hydrocarbon, we designed a 0.5-L spherical phantom showing the theoretically highest possible degree of microscopic anisotropy. Data were acquired on the Connectome scanne...

A phenomenological theory is presented for describing the anisotropic plastic flow of orthotropic polycrystalline aluminum sheet metals under plane stress. The theory uses a stress exponent, a rate-dependent effective flow strength function, and five anisotropic material functions to specify a flowpotential, an associated flow rule of plastic strain rates, a flow rule of plastic spin, and an ev...