نتایج جستجو برای: platelet recovery
تعداد نتایج: 313421 فیلتر نتایج به سال:
BACKGROUND The standard method of assessment of platelet function is represented by light transmission aggregometry (LTA), performed in citrated platelet-rich plasma (PRP). With LTA, decrease and subsequent post-cardiopulmonary bypass (CPB) recovery of platelet function have been reported during cardiac surgery. Multiple electrode aggregometry (MEA) may be used as point-of-care method to monito...
BACKGROUND Studies in murine models suggested that platelet desialylation was an important mechanism of thrombocytopenia during sepsis. METHODS First, we performed a prospective, multicenter, observational study that enrolled septic patients with or without thrombocytopenia to determine the association between platelet desialylation and thrombocytopenia in patients with sepsis, severe sepsis,...
Dear Editor, Dengue is an important arbovirus infection. This infection can result in an acute febrile illness. The important hematological abnormalities included hemoconcentration and thrombocytopenia (1). Due to the decreased platelet count, the patient might develop petechiae and hemorrhagic complication. In endemic area, the presumptive diagnosis of dengue is usually derived by the cl...
It was investigated whether endothelium-derived relaxing factor (EDRF) increases cyclic GMP (cGMP) content in platelets passing through the coronary bed. Boluses of washed platelets from healthy human donors were injected into the aortic perfusion line of isolated, saline-perfused rabbit hearts under constant flow conditions (28 +/- 2 ml/min). The coronary effluent was collected over 5 seconds,...
Hypertransfusion can enhance myeloid recovery after bone marrow depletion, but its influence on thrombopoietic recovery has not been previously defined. We have studied the pattern of platelet and megakaryocyte recovery in mice hypertransfused after receiving 350 rad whole body irradiation. The platelet counts of the hypertransfused group showing an initial fall due to hemodilution in the expan...
Thrombocytopenia in dengue infection raises concerns about bleeding risk. Of 256 patients with dengue infection who developed thrombocytopenia (platelet count, < 20 x 10(3) platelets/microL) without prior bleeding, 188 were given platelet transfusion. Subsequent bleeding, platelet increment, and platelet recovery were similar between patients given transfusion and patients not given transfusion...
1. In heart-lung preparations perfused with heparinized blood, clumping of platelets and a sharp fall in the platelet count occurred in the first 5 to 15 minutes after the external circuit was established. 2. In 10 such preparations surviving from 1 to 4 hours, only one showed a return of the platelet count to the level existing before operation. 3. When platelets were reduced in numbers before...
introduction: this paper used generalized gamma (gg) distribution to find the predictive factors of overall survival (os) after haematopoietic stem cell transplant (hsct) in acute myeloid leukemia patients. methods: discrimination among the exponential, weibull, gg, log-logistic, and lognormal distributions was done using maximum likelihood and akaike information criteria. results: the 5-year ...
OBJECTIVE The platelet storage lesion accelerates platelet clearance after transfusion, but the underlying molecular mechanism remains elusive. Although inhibiting sheddase activity hampers clearance of platelets with storage lesion, the target platelet protein responsible for ectodomain shedding-induced clearance is not definitively identified. Monoclonal antibody 5G6 was developed recently to...
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