Non-paralytic polio (NPP) is commonly thought to be synonymous with "abortive polio," in which the poliovirus neither entered the CNS nor damaged neurons. Described are two epidemic illness -"The Summer Grippe" and Iceland disease -apparently caused by a low virulence but neuropathic type 2 poliovirus, studies showing that neuronal lesions in the brain and spinal cord and muscle weakness were c...

The post-polio syndrome (PPS) is an entity characterized for an episode of muscular weakness and/or abnormal muscular fatigue in individuals that had presented acute polio years before. We report the case of PPS in a patient, 40 years, that thirty-five years after had had paralytic poliomyelitis, developed new symptoms of fatigue, muscular atrophy, dyspnea, difficulties in deambulation and musc...

Poliomyelitis was a dreaded disease of devel­ oped countries, affecting tens of thousands of children and adults during each of the epidemic years up to the mid-1950s. The polio virus is a small RNA virus whose only natural host ap­ pears to be man. The vast majority of exposed persons develop either an inapparent infection or a non-specific flu-like illness (non-paralytic poliomyelitis). Secon...

OBJECTIVE To evaluate changes over time in a clinically based cohort of individuals with post-polio syndrome. DESIGN A prospective longitudinal study. SUBJECTS A total of 106 individuals with poliomyelitis sequelae were included in the study. They were self-referred or had been referred to the post-polio clinic. After 4 years subjects were called for a follow-up and underwent the same measu...

The emergence of vaccine-derived polioviruses (VDPVs) in patients with Primary Immunodeficiency (PID) is a threat to the polio-eradication program. In first its kind pilot study for successful screening and identification VDPV excretion among PID India, enteroviruses were assessed stool specimens 154 across India period two years. A total 21.42% tested positive enteroviruses, 2.59% (PV), wherea...