Monte Carlo simulations were used to investigate the conformational and electrical properties of isolated weak polyelectrolytes in the presence of an oppositely charged particle. Titrations curves were calculated to get an insight into the role of pH on the degree of ionization and conformation of isolated chains. The effect of ionic concentration and polyelectrolyte length on the titration cur...

Background: Polyelectrolyte complexes are complexes formed by interaction of two oppositely charged ions. This study deals with formation of chitosan–Aegle marmelos polyelectrolyte complex. Polyelectrolyte complex was found to be used as pharmaceutical excipient. Aim: The present study aimed to synthesize Chitosan–Aegle marmelos polyelectrolyte complex and their characterization and to compare ...

The objective of this investigation was the development of chitosan/xanthan polyelectrolyte complex based mucoadhesive nasal insert of promethazine hydrochloride a drug used in the treatment of motion sickness. A 32 factorial design was applied for preparing chitosan/xanthan polyelectrolyte complex and to study the effect of independent variables i.e. concentration of xanthan [X1] and concentra...

The objective of this investigation was the development of chitosan/xanthan polyelectrolyte complex based mucoadhesive nasal insert of promethazine hydrochloride a drug used in the treatment of motion sickness. A 32 factorial design was applied for preparing chitosan/xanthan polyelectrolyte complex and to study the effect of independent variables i.e. concentration of xanthan [X1] and concentra...

Complexation between polyelectrolyte and polyampholyte chains in poor solvent conditions for the polyelectrolyte backbone has been studied by molecular dynamics simulations. In a poor solvent a polyelectrolyte forms a necklace-like structure consisting of polymeric globules (beads) connected by strings of monomers. The simulation results can be explained by assuming the existence of two differe...

Dynamic light scattering, static light scattering, and turbidimetry were used to investigate the effect of polyelectrolyte molecular weight and concentration on complex formation between a strong polyelectrolyte, poly(dimethyldially1ammonium chloride) (PDMDAAC), and oppositely charged mixed micelles of Triton X-100 (TX100) and sodium dodecyl sulfate (SDS). The hydrodynamic radius (Rh) of the co...

The affinity of weak polyelectrolyte coated oxide particles to the oil-water interface can be controlled by the degree of dissociation and the thickness of the weak polyelectrolyte layer. Thereby the oil in water (o/w) emulsification ability of the particles can be enabled. We selected the weak polyacid poly(methacrylic acid sodium salt) and the weak polybase poly(allylamine hydrochloride) for ...

Three-dimensional (3-D) structures with micron-sized features have been fabricated via the direct-write assembly of polyelectrolyte inks. By mixing oppositely charged species under solution conditions that promote polyelectrolyte exchange reactions, we have created concentrated fluids capable of flowing through microscale deposition nozzles. Ink deposition into an alcohol/water coagulation rese...

Hybrid modeling approaches based on all-atom force fields to handle a solute and coarse-grained models account for the solvent are promising numerical tools that can be used understand properties of large multi-components solutions thus speed up development new industrial products obey standard green sustainable chemistry. Here, we discuss ability full polarizable hybrid approach coupled molecu...

Polyelectrolyte complexes (PECs) are attractive materials for drug delivery application as they offer simple preparations and high drug-loading efficiency. In this study, a novel method preparing polyelectrolyte complex nanoparticles using s