نتایج جستجو برای: polyhydroxyalkanoate

تعداد نتایج: 737  

Journal: :Bioresource technology 2011
Hideo Akiyama Hiroshi Okuhata Takuo Onizuka Shozo Kanai Masahiko Hirano Satoshi Tanaka Ken Sasaki Hitoshi Miyasaka

A practical antibiotics-free plasmid expression system in cyanobacteria was developed by using the complementation of cyanobacterial recA null mutation with the EscherichiacolirecA gene on the plasmid. This system was applied to the production of polyhydroxyalkanoate (PHA), a biodegradable plastic, and the transgenic cyanobacteria stably maintained the pha genes for PHA production in the antibi...

Journal: :Applied and environmental microbiology 2010
Björn Andreessen Alvin Brian Lange Horst Robenek Alexander Steinbüchel

We have developed the conversion of glycerol into thermoplastic poly(3-hydroxypropionate) [poly(3HP)]. For this, the genes for glycerol dehydratase (dhaB1) of Clostridium butyricum, propionaldehyde dehydrogenase (pduP) of Salmonella enterica serovar Typhimurium LT2, and polyhydroxyalkanoate (PHA) synthase (phaC1) of Ralstonia eutropha were expressed in recombinant Escherichia coli. Poly(3HP) wa...

2014
H.M. Chang Z.H. Wang H.N. Luo M. Xu X.Y. Ren G.X. Zheng B.J. Wu X.H. Zhang X.Y. Lu F. Chen X.H. Jing L. Wang

Development and selection of an ideal scaffold is of importance for tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a biocompatible bioresorbable copolymer that belongs to the polyhydroxyalkanoate family. Because of its good biocompatibility, PHBHHx has been widely used as a cell scaffold for tissue engineering. This review focuses on the utilization of PHBHHx-base...

Journal: :Journal of bacteriology 2001
G M York J Stubbe A J Sinskey

Phasins are proteins that are proposed to play important roles in polyhydroxyalkanoate synthesis and granule formation. Here the phasin PhaP of Ralstonia eutropha has been analyzed with regard to its role in the synthesis of polyhydroxybutyrate (PHB). Purified recombinant PhaP, antibodies against PhaP, and an R. eutropha phaP deletion strain have been generated for this analysis. Studies with t...

2017
Eduarda Morgana da Silva Montenegro Gabriela Scholante Delabary Marcus Adonai Castro da Silva Fernando Dini Andreote André Oliveira de Souza Lima

The use of molecular diagnostic techniques for bioprospecting and microbial diversity study purposes has gained more attention thanks to their functionality, low cost and quick results. In this context, ten degenerate primers were designed for the amplification of polyhydroxyalkanoate synthase (phaC) gene, which is involved in the production of polyhydroxyalkanoate (PHA)-a biodegradable, renewa...

Journal: :Biomaterials 2014
Nina Dinjaski Mar Fernández-Gutiérrez Shivaram Selvam Francisco J Parra-Ruiz Susan M Lehman Julio San Román Ernesto García José L García Andrés J García María Auxiliadora Prieto

Biomaterial-associated infections represent a significant clinical problem, and treatment of these microbial infections is becoming troublesome due to the increasing number of antibiotic-resistant strains. Here, we report a naturally functionalized bacterial polyhydroxyalkanoate (PHACOS) with antibacterial properties. We demonstrate that PHACOS selectively and efficiently inhibits the growth of...

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