Conventional petroleum-derived plastics are recalcitrant to biodegradation and can be problematic as they accumulate in the environment. In contrast, it may be possible to add novel, biodegradable bioplastics to anaerobic digesters at municipal water resource recovery facilities along with primary sludge to produce more biomethane. In this study, thermal and chemical bioplastic pretreatments we...

A novel approach which had foreground of industrialization, surface liquid spraying, was studied in this paper to prepare biodegradable polylactic-co-glycolic acid (PLGA) microspheres for controlled release drug delivery system. To compare with the normal methods, the microspheres prepared by this approach were characterized by particle size distribution and photograph of microscope. The relati...

BACKGROUND Nanoparticles fabricated from the biodegradable and biocompatible polymer, polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug delivery systems. The objective of this study was to explore fully the development of a PLGA nanoparticle drug delivery system for alternative preparation of a commercial formulation. In our nanoparticle fabrication, ou...

The present work describes the synthesis and characterization of PLA-co-EC copolymer from lactic acid and ethyl cellulose by azeotropic dehydration, under reduced pressure, at 140oC for 8 hours. The prepared PLA-co-EC copolymer was used for controlled drug release for an anticancer drug namely 6-Thioguanine with gold nanoparticles. Anticancer drug containing PLAco-EC copolymer nanocapsules were...

Today, the economic consumption of biodegradable polymers is of capital importance in many applications. One of the most commonly used biopolymers is polylactic acid (PLA). The printability of the biodegradable film has not been fully investigated. This work tested the printability of polylactic acid (PLA) films and compared the print qualities to common packaging films like low density pol...

Aim of this work was to compare the efficacy of two loading methods of proteins onto polymeric nanocarriers: adsorption and encapsulation methods. Preliminary studies of protein loading were done using Bovine Serum Albumin (BSA) as model protein. Nanocarriers were prepared starting from polylactic co-glycolic acid (PLGA) polymer; production methods used are two different variants of emulsion ev...

BACKGROUND Squamous cell carcinoma (SCC) is a common skin cancer, and its treatment is still difficult. The aim of this study was to evaluate the effectiveness of nanoparticle (NP)-assisted 5-aminolevulinic acid (ALA) delivery for topical photodynamic therapy (PDT) of cutaneous SCC. MATERIALS AND METHODS Ultraviolet-induced cutaneous SCCs were established in hairless mice. ALA-loaded polylact...

conclusions after paravertebral implantation of rifapentine polylactic acid sustained-release microspheres, the concentration of rifapentine in local vertebral bone tissues was maintained above the tb minimum inhibitory concentration for up to 60 days with no apparent accumulation of the drug in other tissues. methods this study is a basic animal experimental study that began on july 17, 2014 i...

Transcatheter arterial chemoembolization therapy using polylactic acid microspheres containing aclarubicin hydrochloride (ACR) was performed in 62 patients with primary hepatocellular carcinoma. These microspheres were about 200 microns in diameter and contained 10% (w/w) aclarubicin. A single dose of polylactic acid microspheres containing ACR (50-100 mg of ACR) was administered 1 to 8 times w...