The current diagnostic standard procedure outlined by the Health Protection Agency for urinary tract infections (UTIs) in clinical laboratories does not report bacteria isolated from samples containing three or more different bacterial species. As a result many UTIs go unreported and untreated, particularly in elderly patients, where polymicrobial UTI samples are especially prevalent. This stud...

Periodontitis is a polymicrobial infection caused by selected gram-negative bacteria including Porphyromonas gingivalis. Host cell invasion by P. gingivalis has been proposed as a possible mechanism of pathogenesis in periodontitis. The aim of the present study was to assess the influence of periodontopathogens on P. gingivalis invasion of gingival epithelial cells in polymicrobial infection. P...

Parvimonas micra and Provetella oralis are two commensal anaerobic bacteria of the human oral cavity. Anaerobic infections uncommon require a high index suspicion quick start appropriate treatment. We present patient with multifocal infiltrates compatible septic embolism (lung, liver, spleen emboli) polymicrobial bacteremia oralis. Periodontal disease appears to be main cause this disseminated ...

The Gram-negative bacterium Proteus mirabilis is a leading cause of catheter-associated urinary tract infections (CAUTIs), which are often polymicrobial. Numerous prior studies have uncovered virulence factors for P. mirabilis pathogenicity in a murine model of ascending UTI, but little is known concerning pathogenesis during CAUTI or polymicrobial infection. In this study, we utilized five poo...

abstract necrotizing fasciitis is a rare, life-threatening infection most commonly seen in patients with diabetes mellitus, intravenous drug abuse, and immunocompromised conditions. the extremities are the primary sites of involvement in as many as two thirds of the cases. in a significant proportion of patients, the extremities are involved as a result of trauma, needle puncture or extravasati...

conclusions physicians are recommended to take microbiological cultures before starting empirical therapy recommended to cover gram-negative microorganisms in order to lower the risk of antibiotic resistance. objectives the current study aimed to determine the most common microorganisms involved in diabetic foot infection in order to minimize the failure of antibiotic therapy and the risk of de...

OBJECTIVES Infection is a common cause of death among hemodialysis patients. The study investigated incidence, risk factors, clinical features and outcome of bloodstream infections (BSIs) in haemodialysis patients. METHODS The records of haemodialysis patients from 1999 to 2005 were reviewed. Risk factors were investigated by multivariate analysis. RESULTS There were identified 148 bacterem...

Background: We hypothesized that polymicrobial posttraumatic osteomyelitis (PTO) may be associated with worse outcomes when compared to monomicrobial PTO. We therefore attempted to show the outcomes and predisposing factors associated with polymicrobial PTO. Methods: A single-center case-control study was carried out from 2007 to 2012. The outcome variables analyzed were: the need for additiona...

We present a case of COVID-19 complicated by sporotrichosis and fusobacterium blood stream infections - no known prior cases fungemia nor polymicrobial bloodstream in patients. Severe COVID-19, uncontrolled diabetes mellitus (DM), prolonged corticosteroid use contributed to immune dysregulation, increasing the patient's vulnerability infection. This highlights importance vigilance regarding ris...

The role of carbapenem-resistant Acinetobacter baumannii (CRAb) in polymicrobial infection remains elusive. Having observed the ability of CRAb to shelter other susceptible bacteria from carbapenem killing, we sought to determine the factors contributing to this sheltering effect by transforming different recombinant plasmids into recipient A. baumannii cells. The sheltering effects of CRAb wer...