Oxidative stress plays a key role in the pathophysiology of chronic kidney disease (CKD). Most studies have investigated peripheral redox state focus on plasma, but not different immune cells. Our study analyzed several markers plasma and isolated polymorphonuclear (PMNs) mononuclear (MNs) leukocytes from advanced-CKD patients, also evaluating differences hemodialysis (HD) peritoneal dialysis (...

Background: The mammalian target of rapamycin (mTOR) is important in hematopoiesis. Despite the central role of mTOR in regulating the differentiation of immune cells, the effect of mTOR function on cord blood mononuclear cells is yet to be defined. Objectives: To evaluate the effect of mTOR inhibition, using rapamycin on the proliferation and apoptosis of cord blood mononuclear cells, as well ...

Objective: To study whether the generated CD1a positive cells belong to the leukemic cells among patients with juvenile myelomonocytic leukemia. Materials and Methods: We used mononuclear cells from 3 patients with juvenile myelomonocytic leukemia, from which two had monosomy 7. The mononuclear cells from these patients were cultured in RPMI/10%FCS without adding exogeneous growth factors fo...

yet comprehensive text-book and work of reference on Materia Medica, Therapeutics, and a range of cognate subjects. Under head of each drug will be found clear and concise descriptions of its properties and physiological action. In addition chapters will be found on " medical," Latin, pharmacy, table of doses, antidotes and incompatibilities. The volume is based on the United States Pharmacopoe...

Synovial fluid cells in Reiter's syndrome were studied by cell subset specific monoclonal antibodies and avidin-biotin-peroxidase complex staining. Mean leucocyte count was 9842/mm3 (9.842 X 10(9)/l), and 71% of all cells were polymorphonuclear leucocytes. 26 +/- 11 (SEM)% and 47 +/- 5% of all mononuclear cells in synovial fluid were M1+ monocytes and Ia+ cells, respectively. T11+ T lymphocyte ...

Background and Purpose Platelet aggregation plays an important role in the pathogenesis of thromboembolic cerebrovascular disease. Leukocytes can efficiently stimulate as well as inhibit platelet aggregability. We studied the influence of leukocytes on collagen-induced platelet aggregation in patients with acute ischemic stroke. Methods We investigated 23 patients within 2 days after stroke and...

Mononuclear phagocytic leukocytes, as well as polymorphonuclear leukocytes, produce and release superoxide at rest, and this is stimulated by phagocytosis. Of the mouse monocytic cells studied, alveolar macrophages released the largest amounts of superoxide during phagocytosis, followed by normal peritoneal macrophages. Casein-elicited and "activated" macrophages released smaller quantities. In...

Our knowledge of the cell-formula of the lymph is nearly comprised in the statement that small mononuclear elements make it up almost entirely. No systematic differential counts of the lymphcells in man or in other animals are on record. According to the most recent work, that of Weidenreich ( I ) , whose paper is as yet only reported in brief, one finds in the thoracic duct of the rabbit, the ...

Aim: The study's main objective was to see whether the well-known probiotic Bifidobacterium lactis might aid in development of children. Method: A nine-week clinical study involving 400 children aged between 5 10 years, conducted evaluate efficacy food supplementation. Stage 1 participants took 150 ml low-fat milk twice a day for three weeks as baseline diet control. Probiotics (Bifidobacterium...