PURPOSE To validate semiquantitative analysis of positron emission mammography (PEM). METHODS Fifty women with histologically confirmed breast lesions were retrospectively enrolled. Semiquantitative uptake values (4 methods), the maximum PEM uptake value (PUVmax), and the lesion-to-background (LTB) value (3 methods) were measured. LTB is a ratio of the lesion's PUVmax to the mean background; ...

objective(s): in positron emission tomography (pet) studies, thoracic movement under free-breathing conditions is a cause of image degradation. respiratory gating (rg) is commonly used to solve this problem. two different methods, i.e., phase-gating (pg) and amplitude-gating (ag) pet, are available for respiratory gating. it is important to know the strengths and weaknesses of both methods when...

background: gallium-66 (t1/2= 9.49 h) is an interesting radionuclide that has potential for positron emission tomography (pet) imaging of biological processes in intermediate to slow target tissue uptake. oxine has been labeled with this radioisotope in the form of [66ga]gallium chloride for its possible diagnostic properties. materials and methods: 66ga was produced in the 30 mev cyclotron (cy...

With breast cancer incidence rates showing no signs of abating, advances in risk stratification and increasing awareness of cancer control, there is interest in expanding the breast imaging arsenal. Mammography is still the standard of care, and a recent meta-analysis of seven large studies supports its value as a screening tool. There is, however, clear need for improved sensitivity and specif...

Alzheimer's disease is characterized by impaired glucose metabolism and demonstration of amyloid plaques. Individual positron emission tomography tracers may reveal specific signs of pathology that is not readily apparent on inspection of another one. Combination of multitracer positron emission tomography imaging  yields promising results. In this paper, 57 Alzheimer's disease neuroimaging ini...

Introduction. Breast cancer is a major health and economic problem in Serbia. On the one hand, most patients see doctor at an advanced stage of disease, on other screening response rate low. Early detection increases chances survival. Digital mammography gold standard breast imaging, together with supplemental ultrasound tomosynthesis. Mammography combined tomosynthesis has greater regardless d...

Objective(s): To investigate the diagnostic accuracy of positron emission mammography (PEM) and positron emission tomography/computed tomography (PET/CT) for small breast tumors of less than 20 mm in size.Methods: The study was conducted on a total of 100 subjects (i.e., 50 patients with pathologically proven breast cancer and 50 normal cases of medical screening). The total number of tumors wa...