نتایج جستجو برای: post hoc analyses

تعداد نتایج: 804681  

2015
Zach Shahn David Madigan

In randomized experiments, it is often of interest to characterize treatment effect heterogeneity in terms of baseline covariates. Usually, the aim is to identify subpopulations likely to have particularly positive or negative (or neutral) responses to treatment. The process of searching for such subpopulations after the completion of an experiment (without pre-specifying which subpopulations w...

Journal: :The Journal of Thoracic and Cardiovascular Surgery 2016

2016
Nir Giladi Mahnaz Asgharnejad Lars Bauer Frank Grieger Babak Boroojerdi

BACKGROUND Monoamine oxidase B (MAO-B) inhibitors and dopamine receptor agonists are common first-line treatment options in early Parkinson's disease (PD). OBJECTIVE To evaluate the efficacy and safety of rotigotine transdermal patch as an add-on therapy to an MAO-B inhibitor in patients with early-PD. METHODS In two Phase III, randomized, double-blind, placebo-controlled studies in early-P...

2014
Michelle L North Terry J Walker Lisa M Steacy Barnaby G Hobsbawn Richard J Allan Frances Hackman Xiaoqun Sun Andrew G Day Anne K Ellis

BACKGROUND Oral antihistamines that target the histamine receptor-1, such as fexofenadine, offer suboptimal relief of allergic rhinitis-associated nasal congestion. Combinations with oral sympathomimetics, such as pseudoephedrine, relieve congestion but produce side effects. Previous animal and human studies with histamine receptor-3 antagonists, such as PF-03654764, demonstrate promise. METH...

Journal: :Proceedings of the ... AAAI Conference on Artificial Intelligence 2023

Monumental advancements in artificial intelligence (AI) have lured the interest of doctors, lenders, judges, and other professionals. While these high-stakes decision-makers are optimistic about technology, those familiar with AI systems wary lack transparency its decision-making processes. Perturbation-based post hoc explainers offer a model agnostic means interpreting while only requiring que...

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