the goals of post-transplant management are to manage and treat postoperative complications, and develop a balanced long-term immunotherapy regimen that minimizes infection and side effects but controls rejection. while modern immunosuppressant regimes have reduced rates of graft loss due to rejection, they impart major risks for infection, growth failure, metabolic complications, and malignanc...

Introduction Renal transplant is the best treatment of choice for patients with end-stage renal disease (1). Annually, about 17000 patients receive deceased or living donor transplants, which help them promote health and self-efficacy (1-2). However, despite advances in transplant technology, patients face a number of post-operative challenges, which might lead to stress in patients, includin...

background although the immunosuppressant cyclosporine (csa) is widely used after kidney transplantation over the long term, there is still no firm consensus on the best way to monitor of csa blood levels. objectives cyclosporine (csa) assay is critical for the management of renal transplant recipients due to inter– and intra–patient variation in csa absorption and metabolism. patients and meth...

BACKGROUND Recent data suggest that Berlin Heart EXCOR Pediatric (EXCOR) ventricular assist device improves waiting list survival for pediatric heart transplant candidates. Little is known about their post-transplant outcomes. The aim of this analysis was to determine whether there was a difference in early survival for children bridged to transplant with EXCOR versus status 1A pediatric heart ...

BACKGROUND Native nephrectomy (NNx) is often done in patients with autosomal dominant polycystic kidney disease (ADPKD). Controversy exists concerning the need and timing of nephrectomy in transplant candidates. We hypothesize that post-transplant NNx does not negatively impact patient and graft survival. METHODS Among 470 ADPKD transplant recipients included in the study, 114 (24.3%) underwe...

Background—Serum albumin concentration has been recognized as a marker of nutrition, severity of inflammation and hepatic function in patients with various chronic diseases. The purpose of this study was to investigate the impact of pre-transplant serum albumin concentration on post-transplant outcome in heart transplant (HTx) recipients. Methods and Results—Pre-operative laboratory variables i...

The correction of post-transplant hyperlipidaemia warrants the judicious and timely use of pharmacological agents with dietary modification and exercise. Reduction in hyperlipidaemia may have some role in decreasing the incidence of chronic rejection of allografts. The awareness that the morbidity and mortality of atherosclerotic disease may be lowered by active intervention will result in a be...