BACKGROUND Studies of postmenopausal breast cancer have reported positive associations with body size and composition but it is uncertain whether these are due to non-adipose, adipose mass, or central adiposity, and whether they are limited to subgroups defined by age or tumor characteristics. METHODS In a prospective cohort study of women ages 27 to 75, body measurements were taken directly;...

Interest in the years of reproductive changes for women with epilepsy (WWE), specifically perimenopause, menopause and postmenopause has been emerging in the epilepsy community. This article discusses evidence for changes in seizure frequency during perimenopause and postmenopause. Further, a catamenial epilepsy pattern during the reproductive years may be a hallmark for the observed seizure fr...

In our study, 213 healthy Czech women aged 20 to 65 years were examined and divided into fully reproductive, premenopausal, menopausal and postmenopausal groups. In all subjects body composition was determined by classical anthropometry and metabolic profile was assessed. A total of 146 subjects completed 3-year longitudinal study. Total and LDL cholesterol increased and ratio HDL/total cholest...

BACKGROUND After menopause, women exhibit a higher prevalence of the metabolic syndrome (MetS) and higher risk of cardiovascular disease. However, the timing of changes in MetS severity over the menopausal transition and whether these changes differ by racial/ethnic group remain unclear. METHODS AND RESULTS We assessed data from 1470 women from the Atherosclerosis Risk in Communities cohort w...

INTRODUCTION Hormone replacement therapy (HRT) and walking were investigated independently and in combination, to determine which treatment provided most effect on bone turnover in postmenopausal women. METHODS Using a randomised double-blind pilot study, 10 subjects received HRT (transdermal estradiol, 50 μg/day and oral MPA 5 mg/day) and 12 received placebo for 20 weeks. Following a baselin...

UNLABELLED Body weight positively correlates with bone mass, gravity being a stimulating bone stress. Adipose tissues could influence bone metabolism especially in postmenopause. Also, muscle mass positively correlates with bone mass and is dependent on physical activity, but also on some hormones with direct effect on bone, such as insulin growth factor-1 (IGF-1). AIM Our study investigated ...