نتایج جستجو برای: potency test
تعداد نتایج: 835950 فیلتر نتایج به سال:
Based on social cognitive theory (SCT), we develop and test a model that links ethical psychological climate to ethically focused proactive behavior (i.e., voice taking charge) via two distinct mechanisms duty orientation moral potency). Results from multi-wave field studies conducted in the United States, Turkey, France, Vietnam, India demonstrate an indirectly influences employees' charge beh...
a suitable test for potency. Corner's and Allen's' studies on progestational proliferation in the rabbit, resulting from the physiological action of their extract of the corpus luteum, and Hisaw's and Leonard's2 similar results, provided a useful test, but one which had several practical objections, arising primarily from the relatively large size of the test animal, and the consequent expense ...
An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET) at the Federal Institute for Risk Assessment (BfR), and took place on 27–28 April 2009, in Berlin, Germany. The goal of ZEBET is to promote p...
Both European Pharmacopoeia Monograph 01/2008:0447 "Canine Leptospirosis vaccine (inactivated)" and the more recent Monograph 01/2008:1939 "Bovine Leptospirosis vaccine (inactivated)" explicitly allow for a sero-response test to assess batch potency. Test setup and requirements for in vivo and in vitro validation are described. Furthermore, the two main strategies to assess batch potency and th...
An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET) at the Federal Institute for Risk Assessment (BfR), and took place on 27–28 April 2009, in Berlin, Germany. The goal of ZEBET is to promote p...
215 Rabies vaccines for human use currently are tested for potency by a mouse challenge assay. this test was developed by the National Institutes of Health (NIH) and is therefore referred to as the NIH test. Its origins go back to the 1950’s, well before good manufacturing practice (GMP) was established. the NIH test soon was recognized to be highly variable, to consume a large number of animal...
Potency testing of most human and veterinary rabies vaccines requires vaccination of mice followed by a challenge test using an intracerebral injection of live rabies virus. NICEATM, ICCVAM, and their international partners organized a workshop to review the availability and validation status of alternative methods that might reduce, refine, or replace the use of animals for rabies vaccine pote...
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