This paper describes a rapid and accurate method for determining binding abilities of thyroid hormones to their corresponding serum proteins: prealbumin, albumin and thyroxine binding globulin. A tube cell agarose gel electrophoresis is used with radioactive labelled triiodothyronine or thyroxine. The distribution curve shows characteristic peaks for prealbumin, albumin and thyroxine binding gl...

HE term “prealbumin” was originally applied by SMITHIES (1955) to those zones of protein which migrate ahead of albumin in alkaline starch gel. Using acidic starch gel, BRAEND and EFREMOV (1965) and GAHNE (1966) detected numerous protein zones in horse serum that migrated ahead of albumin. Also, FAGERHOL and BRAEND (1965) demonstrated a multiplicity of prealbumin zones in human serum. GAHNE (19...

Amyloid fibrils were isolated from spleen and thyroid obtained at autopsy from one patient (S.K.O.) of Jewish origin with familial amyloidotic polyneuropathy. Gel filtration on Sephadex G100 after solubilization in 5 M guanidine HCl yielded three major components with 14,000, 9,000, and 5,000 mol wt, respectively. The two larger components shared antigenic determinants with human prealbumin. Am...

Amyloid fibrils were concentrated from the kidney, thyroid, and peripheral nerve of six patients with familial amyloidotic polyneuropathy (FAP). The fibril concentrates were solubilized in 6 M guanidine.HCl and fractionated on Sephadex G-100 columns. The elution profile of all FAP amyloid fibril concentrates revealed a protein of apparent Mr of 14,000, designated the FAP protein, that was absen...

We studied 135 premature newborns of 26 to 36 weeks gestation, divided into three groups: the control group, 66 premature infants with uncomplicated course; 51 premature neonates with appropriate birth weight for gestational age (AGA), who suffered from clinical problems that delayed oral feeding; and 18 premature infants with small birth weight for gestational age (SGA). When neonates of the s...

Hospitalized patients who are undernourished are more likely to develop clinical complications and have relatively poor outcomes, with increased length of stay (LOS)1 and higher mortality compared with well-nourished patients. Provision of adequate nutritional support reduces the complication rate and improves outcome (1 ). Considerable efforts have therefore been made to identify patients at r...

state and inflammatory markers in maintenance hemodialysis patients. J Ren Nutr. 2014;24:177–85. 8. Zhang K, Liu L, Cheng X, Dong J, Geng Q, Zuo L. Low levels of vitamin C in dialysis patients is associated with decreased prealbumin and increased C-reactive protein. BMC Nephrol. 2011;12:18. 9. Beck FK, Rosenthal TC. Prealbumin: a marker for nutritional evaluation. Am Fam Physician. 2002;65:1575...

Background: Acute kidney injury (AKI) is associated with increased mortality of in hospital patients. Serum C reactive protein (CRP) is an acute-phase protein markedly increased within hours after infection or inflammation. The relation between inflammation and nutrition is complex. The serum chemistry marker ''prealbumin'' is recommended to assess the nutritional status. In this study, we asse...

Amyloid fibril protein has been isolated from the tissues of a patient of Swedish ancestry with autosomal dominant heredofamilial amyloidosis. After solubilization in guanidine HCl, a significant amount of the protein was contained in a homogeneous low molecular weight fraction. Molecular weight of approximately 14,000, amino acid analysis, double immunodiffusion analysis and immunoelectrophore...

Serum prealbumin is a recognized marker of malnutrition, but its prognostic role in patients with hemorrhagic stroke remains unclear. In this study, we retrospectively reviewed the records of 105 patients with hemorrhagic stroke admitted to Renmin Hospital of Wuhan University, China, from January to December 2015. We collected demographic and radiological data, and recorded serum prealbumin lev...