نتایج جستجو برای: preclinical study

تعداد نتایج: 3992691  

2005
Alexei Deviatov

A few decades ago macroeconomics was a field of its own. Now there is an understanding that macroeconomics should have explicit micro foundations. This project aims to look into several traditional arenas of macroeconomics from the microeconomics standpoint. Specifically, we focus on the role of imperfect information and bounded rationality for the real business cycle, growth, and money.

Journal: :Journal of Neurology, Neurosurgery & Psychiatry 2001

Journal: :Anticancer research 2013
David C Turner Todd D Tillmanns K Elaine Harstead Stacy L Throm Clinton F Stewart

BACKGROUND Combination metronomic topotecan plus pazopanib is active against preclinical models of gynecological cancer. Both agents are substrates for ATP-binding cassette family transporters so there is an increased likelihood for pharmacokinetic (PK) drug-drug interactions. PATIENTS AND METHODS PK analyses of topotecan were performed during three cycles of a phase I dose-escalation study o...

2011
Amedeo Amedei Marisa Benagiano Chiara della Bella Elena Niccolai Mario M. D'Elios

Gastric cancer (GC) is the fourth most common cancer and the second most frequent cause of cancer-related deaths, accounting for 10.4% of cancer deaths worldwide. Despite the improvements, estimated cure rates for patients with advanced stages remain poor, and in the metastatic setting, chemotherapy is the mainstay of palliative therapy and results in objective response rates (ORRs) of only 20-...

Journal: :Frontiers in bioscience 2012
Arantxa Perez-Garcia Josefa Carrion-Navarro Minerva Bosch-Fortea Elisa Lazaro-Ibanez Ricardo Prat-Acin Angel Ayuso-Sacido

Glioblastoma multiforme (GBM) is the most aggressive brain tumor in the adult human, with an average survival of 16 months. A small population of cells within the GBM termed cancer-initiating cells is responsible for the initiation and maintenance of the tumor mass. The traditional glioblastoma cancer cells, grown with serum containing media, display increased rate of genomic instability events...

2017
Adem Nadjib Hadj Boussaad

......................................................................................................................................... ii Author’s Contributions ............................................................................................................... iii Acknowledgements .......................................................................................................

ABDIWALI KEYNAN, AMINAH SHAH, JESSE RAMEY, MANISH MANOHAR SATEESH ARJA SHIVAPRAKASH BAYAPALLI, SIREESHA BALA A TARIG AHMED YOGESH ACHARYA,

Introduction: The standardized Patient Program (SPP) is astandard educational training method which provides the preclinicalstudents a better clinical foundation by linking the realmof clinical medicine to basic sciences. It incorporates a modernsimulation technique and enhances the ability of the studentswherein they can practice, apply and learn the basics of patientencounter. The main object...

B. Nematdoost Hagi L. Mousavi Dehmourdi M. Banaee, M. Mohiseni V. Soleimany

The current study was done to investigate the preclinical safety and toxicology of Althaea officinalis extract as naturopathic medicine in common carp (Cyprinus carpio). Specimens were treated with 0 (control), 2.5, 5 and 10 g of marshmallow extract for 45 days. Plasma biochemical parameters were measured after 15 and 45 days. Total protein, albumin and globulin levels (p < /em>>0.05). During t...

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