نتایج جستجو برای: predictive biomarker

تعداد نتایج: 196512  

Journal: :Cancer Epidemiology Biomarkers & Prevention 2010

Journal: :Multiple Sclerosis Journal - Experimental, Translational and Clinical 2020

Journal: :Arthritis Research & Therapy 2009
Wolfgang Hueber Beren H Tomooka Franak Batliwalla Wentian Li Paul A Monach Robert J Tibshirani Ronald F Van Vollenhoven Jon Lampa Kazuyoshi Saito Yoshiya Tanaka Mark C Genovese Lars Klareskog Peter K Gregersen William H Robinson

INTRODUCTION Anti-TNF therapies have revolutionized the treatment of rheumatoid arthritis (RA), a common systemic autoimmune disease involving destruction of the synovial joints. However, in the practice of rheumatology approximately one-third of patients demonstrate no clinical improvement in response to treatment with anti-TNF therapies, while another third demonstrate a partial response, and...

2015
Rebecca M Østervig Lars Køber Jakob L Forberg Lars S Rasmussen Jesper Eugen-Olsen Kasper Iversen

Background Efficient triage in the Emergency Departments (ED) is important to identify patients in need of urgent care. Biomarker measurements may aid these clinical decisions. suPAR, soluble urokinase-type plasminogen activator receptor, is a non-specific biomarker reflecting inflammation and is a strong prognostic marker for several diseases. This study investigated suPAR’s predictive capacit...

Journal: :Brain, Behavior, and Immunity 2016
Frieder Haenisch Jason D. Cooper Andreas Reif Sarah Kittel-Schneider Johann Steiner F. Markus Leweke Matthias Rothermundt Nico J.M. van Beveren Benedicto Crespo-Facorro David W. Niebuhr David N. Cowan Natalya S. Weber Robert H. Yolken Brenda W.J.H. Penninx Sabine Bahn

BACKGROUND Bipolar disorder (BD) is a costly, devastating and life shortening mental disorder that is often misdiagnosed, especially on initial presentation. Misdiagnosis frequently results in ineffective treatment. We investigated the utility of a biomarker panel as a diagnostic test for BD. METHODS AND FINDINGS We performed a meta-analysis of eight case-control studies to define a diagnosti...

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