In this review, we evaluate the different modalities of embryo genetic testing including preimplantation for aneuploidy (PGT-A), monogenic/single-gene abnormalities (PGT-M), and chromosomal structural rearrangements (PGT-SR), with a clinical focus on indications, strengths, limitations, parameters each technique. Articles were obtained from PubMed American College Obstetricians Gynecologists So...

In 2005, the European Society for Human Reproduction and Embryology (ESHRE) Preimplantation Genetic Diagnosis (PGD) Consortium published a set of Guidelines for Best Practice to give information, support and guidance to potential, existing and fledgling PGD programmes (Thornhill AR, De Die-Smulders CE, Geraedts JP, Harper JC, Harton GL, Lavery SA, Moutou C, Robinson MD, Schmutzler AG, Scriven P...

In 2005, the European Society for Human Reproduction and Embryology (ESHRE) Preimplantation Genetic Diagnosis (PGD) Consortium published a set of Guidelines for Best Practice to give information, support and guidance to potential, existing and fledgling PGD programmes (Thornhill AR, De Die-Smulders CE, Geraedts JP, Harper JC, Harton GL, Lavery SA, Moutou C, Robinson MD, Schmutzler AG, Scriven P...

bjective: To review a 12-year experience of the world’s three largest preimplantation genetic diagnosis PGD) centers. esign: Multicenter analysis of the clinical outcome of PGD. etting: In vitro fertilization programs at the Reproductive Genetics Institute, Chicago, Illinois; Saint arnabas Medical Center, West Orange, New Jersey; and SISMER, Bologna, Italy. atient(s): Poor-prognosis IVF patient...

Background: During the last half of the twentieth century, there were a series of advancements in reproductive medicine and genetic testing. Preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS) are the two main methods of preconception genetic testing. The purpose of this article is to present the existing literature regarding the patients’ attitudes towards PGD a...