We report a case of Eikenella corrodens sepsis associated with CSF pleocytosis in a very low birth weight neonate. A 1000-gram male neonate was born at 27-week gestation due to preterm labor. The patient presented with signs and symptoms of sepsis and was treated for suspected meningitis with intravenous ampicillin and gentamicin for 7 days, with cefotaxime added for three weeks. He had a norma...

pulmonary haemorrhage (pH) in a sick neonate is a life-threatening complication and is often associated with a high mortality. it is now often seen in extreme preterm and very low birth weight infants who are growth restricted and have received surfactant with significant respiratory distress syndrome. the mainstay of treatment includes ventilation and vigorous resuscitation of a shocked and cr...

Respiratory support improvements have aided survival of premature neonates, but infection susceptibility remains a predominant problem. We previously reported that neonatal mice have a rapidly evolving T-cell receptor (TCR) repertoire that impairs CD8+ T cell immunity. To understand the impact of prematurity on the human CD8+ TCR repertoire, we performed next-generation sequencing of the comple...

We report a successful closure of large patent ductus arteriosus (PDA) in low-birth weight preterm neonate using an ADO IIdevice for the first time AFIC/NIHD Rawalpindi. A hemodynamically significant PDA carries anincreased risk morbidity, including chronic lung disease, necrotizing enterocolitis and renal impairment. After failure ofmedical therapy, successful, timely safe transcatheter approp...

The results of several clinical trials suggest that infants born depressed can be successfully resuscitated with room air. In 2010, the American Heart Association, American Academy of Pediatrics, Neonatal Resuscitation Program, and the International Liaison Committee published new guidelines to initiate the resuscitation of the term neonate with 21% oxygen. Although this recommendation cannot b...

background: nasal continuous positive airway pressure (ncpap) is an effective method of ventilation in newborns with respiratory distress syndrome (rds). using an appropriate nasal skin care protocol is identical to prevention or reduction of nasal skin breakdown in those who receive ncpap. this study aimed to investigate the effectiveness of an evidence-based clinical care protocol on nasal sk...

Pericardial effusion with cardiac tamponade is a rare and life-threatening complication of peripherally inserted central catheter (PICC) in a neonate. We report a 33-week preterm neonate who had sudden clinical deterioration at day seven of total parenteral nutrition regime via PICC. Recognition of pericardial effusion with cardiac tamponade in neonates with a PICC requires a high index of susp...

Herein, we report the draft genome sequence of Staphylococcus warneri ED-NGS-1001, cultivated from a blood sample taken from a preterm neonate blood sepsis patient at the Royal Infirmary, Edinburgh, Scotland, United Kingdom.