Apoptosis, or programmed cell death, involves a cascade of regulatory events leading to the activation of specific proteases. However, the key substrates for these proteases remain to be identified. We previously demonstrated that levels of five unidentified polypeptides were specifically increased in neurons from embryonic chicken ciliary ganglia undergoing apoptosis by trophic deprivation. He...

background: the aim of this study was to investigate the preventive effect of the polyamine component n, n, n´, n´-tetrakis(2-aminoethyl)2,2-dimethylpropane-1,3-diamine (tdmtn) on apoptotic motor neurons in adult mouse spinal cord slices. materials and methods: thoracic region of adult mouse spinal cords was sliced by a tissue chopper into 400 μm slices and cultured in medium in the presence or...

introduction: tegrity is the most important component for transferring genetic information sperm dna fragmentation is considered a component of male infertility. its assessment comprises conventional semen analysis of which emphasis is placed on its evaluation in fertility clinics. in this study, we investigate the relationship between sperm parameters of motility, morphology, concentration, an...

this study analyzed the determinants of the productivity of smallholder arable crop farmers with a particular focus on land fragmentation using the simpson index as measures of land fragmentation in imo state of nigeria. data collected by using structured questionnaire and interview schedules were analyzed using simple descriptive statistics; simpson index and regression analysis. results showe...

IPv4 fragmentation is not sufficiently robust for use under some conditions in today’s Internet. At high data rates, the 16-bit IP identification field is not large enough to prevent frequent incorrectly assembled IP fragments, and the TCP and UDP checksums are insufficient to prevent the resulting corrupted datagrams from being delivered to higher protocol layers. This note describes some easi...

OBJECTIVE To assess the fragmentation (ablation) efficiency of laser lithotripsy along a wide range of pulse energies, frequencies, power settings and different laser fibres, in particular to compare high- with low-frequency lithotripsy using a dynamic and innovative testing procedure free from any human interaction bias. MATERIALS AND METHODS An automated laser fragmentation testing system w...

Serum-free PC12 cell cultures have been used to study the mechanisms of neuronal death after neurotrophic factor deprivation. We previously reported that PC12 cells undergo "apoptotic" internucleosomal DNA cleavage after withdrawal of trophic support. Here, we have used a sensitive method to detect PC12 cell DNA fragmentation within three hrs of serum removal and have exploited this assay to ex...

Background Sperm DNA fragmentation is known as an important cause of male infertility. The influence of sperm DNA damage on reproductive potential has been subject of many studies indicating various results and remaining the subject controversial. In this study, we investigated differences of the semen parameters and intracytoplasmic sperm injection (ICSI) outcome according to sperm DNA fragmen...

We calculate the exact fragmentation functions for c and b quark fragmentation taking into account the spin orientation of the initial heavy quark in the form of analytical and rather simple expressions. Our calculations show that spin orientation may have an important effect on the fragmentation spectrum. This effect is more striking in the cases of c ?D, D*; c? ? , ? , and ?B , B *.