BACKGROUND Axillary hyperhidrosis is a common but difficult-to-treat condition with major social, labor, and emotional consequences. OBJECTIVE The aim of this study is to present the Nd-YAG laser as a safe and effective option for the treatment of axillary hyperhidrosis. MATERIALS AND METHODS From January 2002 to April 2007, 17 patients (15 women and 2 men) with axillary hyperhidrosis were ...

Hyperhidrosis is a common disorder that may have a severe impact on quality of life. The aim of this study was to investigate the clinical effect of two novel botulinum toxins, Xeomin®, a type A botulinum toxin, and Neuro-bloc®, a type B botulinum toxin, in the treatment of axillary and palmar hyperhidrosis. A total of 84 patients, 58 with axillary and 26 with palmar hyperhidrosis, were include...

Background: Clinical trials of primary axillary hyperhidrosis (AHH) require rigorous measurement AHH severity from the patient’s perspective. Previously, we reported conceptualization and item content development for Hyperhidrosis Disease Severity Measure-Axillary (HDSM-Ax) scale. Objective: To evaluate psychometric performance estimate clinically meaningful change scores HDSM-Ax in a Phase IIb...

BACKGROUND Duration of effect and effectiveness limit current options for treating axillary hyperhidrosis. A new microwave procedure for treatment of axillary hyperhidrosis has been tested. STUDY DESIGN/MATERIALS AND METHODS Adults with primary axillary hyperhidrosis were enrolled in a randomized, sham-controlled, blinded study. Subjects were required to have a Hyperhidrosis Disease Severity ...

OBJECTIVE The objective was to demonstrate that botulinum toxin type A (BTX-A) can be delivered to targeted skin sites with topical application for the treatment of primary axillary hyperhidrosis. METHODS This randomized, blinded, vehicle-controlled study enrolled 12 patients with primary axillary hyperhidrosis with greater than 50 mg of sweat produced per 5 minutes. BTX-A (200 U), combined w...

CONTEXT Essential hyperhidrosis is a frequent disorder causing significant functional impairment. The advent and development of video-assisted thoracoscopic techniques now allows thoracic sympathectomy to be carried out precisely and safety with good results and minimal morbidity. OBJECTIVE To assess the impact of video-assisted thoracic sympathectomy in patients diagnosed as presenting sever...

BACKGROUND Endoscopic bilateral thoracic sympathicolysis (EBTS) is an effective and minimally invasive procedure used for patients with primary hyperhidrosis. The purpose of this study was to examine plantar hyperhidrosis before and after EBTS. METHODS A total of 198 patients with primary hyperhidrosis underwent 396 thoracoscopic sympathicolysis of ganglia T2-T3 in a prospective study. All co...

Primary focal hyperhidrosis is a common disorder for which treatment is often a therapeutic challenge. A systematic review of current literature on the various treatment modalities for primary focal hyperhidrosis was performed and a step-by-step approach for the different types of primary focal hyperhidrosis (axillary, palmar, plantar and craniofacial) was established. Non-surgical treatments (...

OBJECTIVE To evaluate the safety and efficacy of botulinum toxin type A (BTX-A) (BOTOX) over 16 months in the treatment of bilateral primary axillary hyperhidrosis. DESIGN A 16-month study with initial double-blind randomization to 50 U of BTX-A or placebo per axilla. After 4 months, participants could receive up to 3 further treatments with open-label BTX-A over 12 months. SETTING Fourteen...

OBJECTIVES To evaluate the safety and efficacy of botulinum toxin type A in the treatment of bilateral primary axillary hyperhidrosis. DESIGN Multicentre, randomised, parallel group, placebo controlled trial. SETTING 17 dermatology and neurology clinics in Belgium, Germany, Switzerland, and the United Kingdom. PARTICIPANTS Patients aged 18-75 years with bilateral primary axillary hyperhid...