نتایج جستجو برای: primidone
تعداد نتایج: 231 فیلتر نتایج به سال:
Background: Primidone is effective in the treatment of epilepsy. In this research, effect of primidone on liver- related biochemical factors in adult male rats was studied. Material and Methods: For this purpose, 40 adult male wistar rats, weighing approximately 180-200 g were divided into 5 groups of 8 animals. Groups: control group, Sham group and treatment at doses of 20 ,40 and 60 mg/kg, or...
Cognitive functions evaluated by P300 and visual and auditory number assays in children with childhood epilepsy with occipital paroxysms (CEOP) Case Reports Is primidone the drug of choice for epileptic patients with QT-prolongation? A comprehensive analysis of literature
Primidone has been a valuable drug in the treatment of epilepsy since the early 1950's. It is akin to phenobarbitone (see Fig.) in which the carbon atom at the 'two' position in the pyrimidine ring has two hydrogens instead of a carbonyl oxygen. Bogue and Carrington developed the drug in 1949, and reported on its effectiveness in experimental animals (Bogue and Carrington, 1953). Clinical trial...
We describe a simple liquid-chromatographic system for simultaneously measuring bronchodilators, anticonvulsants, hypnotics, and chloramphenicol. Use in therapeutic drug monitoring includes determination of theophylline, caffeine, chloramphenicol, ethosuximide, primidone, phenobarbital, phenacemide, phenytoin, mephenytoin, nirvanol, and carbamazepine and its bioactive metabolites within 13 min....
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