PURPOSE/OBJECTIVES To describe the experience of being a pain resource nurse (PRN), discuss the influence of the PRN's role on colleagues and patient care, and explore barriers to the PRN role. DESIGN Qualitative, exploratory. SETTING A Veterans Administration hospital in the southeastern United States. SAMPLE 12 nurses who received advanced training in pain assessment and management atte...

In this paper, we describe the Parallel Race Network (PRN), a race model with the ability to learn stimulus–response associations using a formal framework that is very similar to the one used by the traditional connectionist networks. The PRN assumes that the connections represent abstract units of time rather than strengths of association. Consequently, the connections in the network indicate ...

The Packet Radio Network (PRN) is an attractive architecture to support mobile and wireless communication. Although the code assignment problem has been studied extensively on PRN, we observe in this paper that the power control problem has been ignored by most works, but may have significant impact on performance. By power control, we mean that the transmission ranges of stations are tunable. ...

PURPOSE To evaluate the safety and efficacy of intravitreal ranibizumab for macular edema secondary to central retinal vein occlusion. METHODS Patients with macular edema secondary to perfused central retinal vein occlusion were enrolled in this ongoing, prospective, open-label study. Treatment was initiated with monthly intravitreal ranibizumab for 3 months. In the first year, additional inj...

BACKGROUND To investigate whether treatment as required 'pro re nata' (PRN) versus regular monthly treatment regimens lead to differences in outcomes in neovascular age-related macular degeneration (nAMD). Regular monthly administration of vascular endothelial growth factor (VEGF) inhibitors is an established gold standard treatment, but this approach is costly. Replacement of monthly by PRN tr...

INTRODUCTION Various factors play a role in the development of erectile dysfunction (ED). AIM To provide a descriptive comparison of erectile function response for tadalafil on-demand (PRN) and once-daily (OAD) dosing regimens in patients with common comorbid conditions, treatments, or risk factors that can be considered when treating ED. METHODS In total, 17 PRN and 4 OAD placebo-controlle...

PURPOSE To evaluate intravitreal aflibercept injections (IAI; also called VEGF Trap-Eye) for patients with macular edema secondary to central retinal vein occlusion (CRVO). DESIGN Randomized controlled trial. METHODS This multicenter study randomized 189 patients (1 eye/patient) with macular edema secondary to CRVO to receive 6 monthly injections of either 2 mg intravitreal aflibercept (IAI...

BACKGROUND Treat and extend (TE) treatment regimens have the potential to reduce the treatment burden placed upon patients receiving ranibizumab for neovascular age-related macular degeneration (nAMD). This study aimed to analyse changes in best corrected visual acuity (BCVA) and anatomical parameters in patients switching from a pro re nata (PRN) to a TE regimen during routine clinical practic...