Background: Progesterone is essential for establishing and maintaining a pregnancy. However, premature atresia of the corpus luteum (CL) or sub-optimal progesterone secretion after ovulation may result in decreased ability to establish maintain The current limitations serum hormone testing fail give complete picture production across luteal phase required

There is controversy about the beneficial effects of topical progesterone creams used by postmenopausal women. A major concern is that serum progesterone levels achieved with progesterone creams are too low to have a secretory effect on the endometrium. However, antiproliferative effects on the endometrium have been demonstrated with progesterone creams when circulating levels of progesterone a...

Acute application of progesterone attenuates cardiac contraction, although the underlying mechanisms are unclear. We investigated whether progesterone modified contraction in isolated ventricular myocytes and identified the Ca2+ handling mechanisms involved in female C57BL/6 mice (6-9 mo; sodium pentobarbital anesthesia). Cells were field-stimulated (4 Hz; 37°C) and exposed to progesterone (0.0...

A. PR expression and regulation IV. Progesterone Regulation of Gene Expression in the Uterus, Ovary, and Chick Oviduct A. Progesterone effects on proliferation and decidu-alization in the uterus during the menstrual cycle B. Progesterone regulation of insulin-like growth factor (IGF) pathways in the endometrium C. Control of ovulation D. Implantation, uterine proliferation, and early pregnancy ...

i read with interest the papers written by peyghambari et al (2008) and niknafs et al   nd   et al   et al   et al   et al   et al   et al   et al   (1994) did not observe any   advantage in the pregnancy rates when adding estrogen+progesterone at luteal phase in patients undergoing ivf (6). in conclusion, the mechanism of luteal phase support in assisted reproduction is complex and a controver...

Background: The role of estrogen and progesterone in stroke is suggested in previous studies, but yet is controversial. Objectives: Comparing the plasma levels of estrogen and progesterone and their ratio in ischemic stroke patients and healthy population. Materials and Methods: This cross-sectional comparative study was conducted from March to September of 2013. Sixty-six female patients older...

A possible involvement of gender-dependent factors has been postulated in development of human non-small-cell lung cancers (NSCLC), but its details remain unclear. In this study, we examined biological significance of progesterone receptor in NSCLCs. Progesterone receptor immunoreactivity was detected in 106 of 228 NSCLCs (46.5%). Progesterone receptor-positive NSCLC was frequently detected in ...

background: progesterone as a sex steroid hormone is thought to affect and prevent demyelination, but its role in promoting myelin repair is far less investigated. in this study, remyelinating potential of progesterone in corpus callosum was evaluated on an experimental model of ms. methods: in this experimental study, adult male c57bl/6 mice were fed with 0.2% (w/w) cuprizone in ground breeder...