To the Editor: Herrmann-Storck et al. (1) investigated prognostic factors of leptospirosis and concluded that infection with Leptospira interrogans serovar Icterohemorrhagiae was linked to severe outcomes. We have concerns about this conclusion. These researchers were comparing clinical severity of disease among patients for whom serovars of infecting isolates had been identifi ed. However, in ...

Methods: There were 113 AIS patients (95 females and 18 males) who had a curve of more than 40 degrees at the time of presentation, with an average age of 12 years and 10 months. We measured RVA on the convex and concave sides at the apex and 12th vertebrae and measured rib-vertebral angle difference (RVAD) using Mehta's method at each follow-up. We also measured the drooping value of the conve...

Background: The breast cancer is the most prevalent cancer among women, on the other hand absence of myoepithelial cells play a pivotal role in pathogenesis of this cancer. Thus we aimed to investigate the possible abilities of the molecular assay technique to find a relationship between mammary serine protease inhibitor (Maspin) gene expression possibly secreted by my...

The receptor and the receptor axis CXCL12 / CXCR4 are the two pairs studied in the metastasis of breast cancer. The purpose of this study was to investigate the relationship between the occurrence of CXCR4 / CXCL12 genes polymorphism and the clinical and pathological characteristics of patients with metastatic breast cancer under chemotherapy. Material and methods: Genomic DNA was extracted f...

preeclampsia is an important pregnancy disorder with serious maternal and fetal complications which its etiology has not been completely understood yet. early diagnosis and management of disease could reduce its potential side effects. the vascular endothelial growth factor (vegf) family including vegf-a is the most potent endothelial growth factor which induces angiogenesis and endothelial cel...

aim : the aim of this study was to compare prognostic factors between colon and rectal cancers. background : prognosis of colorectal cancer (crc) may depend on the anatomical site. patients and methods : a total of 1219 patients with crc diagnosis according to the pathology report of rcgld cancer registry, from 1 january 2002 to 1 october 2007, were entered into the study. demographic and clini...

background: thymomas are rare epithelial tumors arising from thymus gland. this study aims at investigating the clinical presentation, prognostic factors and treatment outcome of forty five patients with thymoma and thymic carcinoma. methods: forty-five patients being histologically diagnosed with thymoma or thymic carcinoma that were treated and followed-up at a tertiary academic hospital duri...