Programmed cell death is an integral component of Caenorhabditis elegans development. Genetic and reverse genetic studies in C. elegans have led to the identification of many genes and conserved cell death pathways that are important for the specification of which cells should live or die, the activation of the suicide program, and the dismantling and removal of dying cells. Molecular, cell bio...

Programmed cell death is essential for plant development and stress adaptation. A detailed understanding of the signal transduction pathways that regulate plant programmed cell death requires identification of the underpinning protein networks. Here, we have used a protagonist and antagonist of programmed cell death triggered by fumonisin B1 as probes to identify key cell death regulatory prote...

Programmed cell death is an important process during the development and life of multicellular organisms. The process by which many cell types undergo programmed cell death is morphologically and mechanistically similar and has been termed apoptosis. To understand how cells achieve this conserved cell-death fate, we have analyzed the genetic control of downstream events in the cell-death proces...