PURPOSE. The migration, proliferation, differentiation, and adhesion of cells and other cellular functions are influenced by the surrounding extracellular matrix, in normal and wound-healing conditions. The matrix metalloproteinases (MMPs) are a family of enzymes that degrade and remodel the extracellular matrix and, thus, play a central role in the wound-healing process. Proliferative vitreore...

tribulus terrestris (tt) is a member of the zygophyllaceae family. traditional chinese medicine recommends the use of tt for treatment of a variety of diseases. in the present study we further investigated anti-proliferative and cytotoxic effects of tt extract on normal and several malignant cell lines. for this purpose, ttwas collected and after authentication, aqueous extract was prepared. cy...

cytokines influence cell cycle events, which in some but not all instances can be associated with melanoma progression. analysis of the g0/g 1 and s phase fractions of the cell cycle was used to assay the proliferative or inhibitory activity of cytokines against ten human melanoma cell lines, including pairs of cell lines derived from primary and metastatic tissue of individual patients. cytoki...