The accumulation of proline in anthers of Petunia was followed during flower bud development. Accumulation proceeded continuously from the microspore stage to anthesis except for an intervening period when bud length was between 15 and 35 mm. The second rise in proline content co­ incided with the stage of anther desiccation. The metabolism of proline 3 lA was studied in isolated branches fed w...

Aim. Analysis of physiological and biochemical characteristics genetically modified wheat with partially suppressed activity the proline dehydrogenase gene. Methods. Determination (PDH) activity, free L-proline (Pro); carbohydrate content (sucrose fructose). Results. It was established that under conditions water deficit in plants integrated elements forming double-stranded RNA suppressor pdh g...

BACKGROUND Transforming growth factor-beta(1) (TGF-beta(1)) contributes to arterial remodeling by stimulating vascular smooth muscle cell (VSMC) growth and collagen synthesis at sites of vascular injury. Because L-arginine is metabolized to growth-stimulatory polyamines and to the essential collagen precursor L-proline, we examined whether TGF-beta(1) regulates the transcellular transport and m...

Proline metabolism is critical for cellular response to microenvironmental stress in living organisms across different kingdoms, ranging from bacteria, plants animals. In bacteria and plants, proline known accrue osmotic other stresses. higher such as human, plays important roles physiology well pathological processes including cancer. The importance of diseases lies the fact that products are ...

The metabolism of lactate to pyruvate in the mediobasal hypothalamus (MBH) regulates hepatic glucose production. Because astrocytes and neurons are functionally linked by metabolic coupling through lactate transfer via the astrocyte-neuron lactate shuttle (ANLS), we reasoned that astrocytes might be involved in the hypothalamic regulation of glucose metabolism. To examine this possibility, we u...

Plant adaptation to abiotic stresses such as drought and salinity involves complex regulatory processes. Deciphering the signaling components that are involved in stress signal transduction and cellular responses is of importance to understand how plants cope with salt stress. Accumulation of osmolytes such as proline is considered to participate in the osmotic adjustment of plant cells to sali...

Proline metabolism has an underlying role in apoptotic signaling that influences tumorigenesis. Proline is oxidized to glutamate in the mitochondria, with the rate-limiting step catalyzed by proline dehydrogenase (PRODH). PRODH expression is inducible by p53, leading to increased proline oxidation, reactive oxygen species formation, and induction of apoptosis. Paradoxical to its role in apoptos...