نتایج جستجو برای: promiscuity
تعداد نتایج: 1776 فیلتر نتایج به سال:
Catalytic promiscuity plays a key role in enzyme evolution and the acquisition of novel biological functions. Because of the high reactivity of radical species, in our view enzymes involving radical-mediated mechanisms could intrinsically be more prone to catalytic promiscuity. This mini-review summarizes the recent advances in the study of NosL, a radical S-adenosyl-L-methionine (SAM)-dependen...
Background: Promiscuity and attitude towards infidelity can harm family health cause many problems. They are also two important reasons for divorce separation. This study aimed to investigate the association of emotional cognitive intimacy with promiscuity through mediating role in married men. Methods: applied descriptive had a correlational design adopted structural equation modeling method. ...
Substrate specificity and selectivity of a biocatalyst are determined by the protein sequence and structure of its active site. Finding versatile biocatalysts acting against multiple substrates while at the same time being chiral selective is of interest for the pharmaceutical and chemical industry. However, the relationships between these two properties in natural microbial enzymes remain unde...
Most eukaryotic proteins are composed of two or more domains. These assemble in a modular manner to create new proteins usually by the acquisition of one or more domains to an existing protein. Promiscuous domains which are found embedded in a variety of proteins and co-exist with many other domains are of particular interest and were shown to have roles in signaling pathways and mediating netw...
Members of enzyme superfamilies specialize in different reactions but often exhibit catalytic promiscuity for one another's reactions, consistent with catalytic promiscuity as an important driver in the evolution of new enzymes. Wanting to understand how catalytic promiscuity and other factors may influence evolution across a superfamily, we turned to the well-studied alkaline phosphatase (AP) ...
Understanding causes of variation in promiscuity within populations remain a major challenge. While most studies have focused on quantifying fitness costs and benefits of promiscuous behaviour, an alternative possibility--that variation in promiscuity within populations is maintained because of linkage with other traits-has received little attention. Here, we examine whether promiscuity in male...
To facilitate work in discourse interpretation, the logical form of English sentences should be both close to English and syntactically simple. In this paper i propose s logical notation which is first-order and uonintensional, sad for which semantic tnmsla-tion can be naively compositional. The key move is to expand what kinds of entities one allows in one's ontology, rather than complicating ...
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