objective(s): adipose derived stem cells (adscs) can be engineered to express bone specific markers. the aim of this study is to evaluate repairing tibia in animal model with differentiated osteoblasts from autologous adscs in alginate scaffold. materials and methods: in this study, 6 canine’s adscs were encapsulated in alginate and differentiated into osteoblasts. alkaline phosphatase assay (a...

This study was aimed to determine abundance and body distribution of PRM in laying hens of Arak. A total of 1400 laying hens were randomly examined from January to June 2008. Of those, 26 (92.86%) layer farms were found to be infested with Dermanyssus gallinae (39.3%). There was significant association between prevalence and climatic conditions of the region. The most common predilection site o...

BACKGROUND We evaluated the commutability of a proposed reference material (PRM), with a formulation based on dilution of Certified Reference Material 470 (CRM470), for 24 high-sensitivity C-reactive protein (hsCRP) methods. We also investigated whether calibration by use of PRM was effective in harmonizing results. METHODS A set of 40 native clinical samples was measured along with PRM and 3...

this study was aimed to determine abundance and body distribution of prm in laying hens of arak. a total of 1400 laying hens were randomly examined from january to june 2008. of those, 26 (92.86%) layer farms were found to be infested with dermanyssus gallinae (39.3%). there was significant association between prevalence and climatic conditions of the region. the most common predilection site o...

Parametric response mapping (PRM) of inspiration and expiration computed tomography (CT) images improves the radiological phenotyping of chronic obstructive pulmonary disease (COPD). PRM classifies individual voxels of lung parenchyma as normal, emphysematous, or nonemphysematous air trapping. In this study, bias and noise characteristics of the PRM methodology to CT and clinical procedures wer...

Embryonic stem cells (ESCs) generated from the in-vitro culture of blastocyst stage embryos are known as equivalent to blastocyst inner cell mass (ICM) in-vivo. Though several reports have shown the expression of germ cell/pre-meiotic (GC/PrM) markers in ESCs, their functional relevance for the pluripotency and germ line commitment are largely unknown. In the present study, we used mouse as a m...

BACKGROUND Add-on prolonged-release melatonin (PRM) in antihypertensive therapy has been shown to ameliorate nocturnal hypertension. Hypertension is a major comorbidity among insomnia patients. The efficacy and safety of PRM for primary insomnia in patients aged 55 years and older who are treated with antihypertensive drugs were evaluated. METHODS Post hoc analysis of pooled antihypertensive ...

BACKGROUND Prolonged-release melatonin (PRM) 2 mg is indicated for insomnia in patients aged 55 years and older. A recent double-blind placebo-controlled study demonstrated 6-month efficacy and safety of PRM in insomnia patients aged 18-80 and lack of withdrawal and rebound symptoms upon discontinuation. OBJECTIVE To investigate the efficacy, safety, and withdrawal phenomena associated with 6...